1-Azakenpaullone

Name: 1-Azakenpaullone
SKU: A14303

目录号: A14303

GSK-3β 抑制剂

1-Azakenpaullone Chemical Structure

CAS NO. 676596-65-9

1-Azakenpaullone是一种有效的选择性GSK-3β抑制剂，IC50为18 nM，选择性比CDK1/cyclin B和CDK5/p25高100倍。

库存：现货

规格	价格	数量
2 mg	￥ 1,200.00
5 mg	￥ 2,370.00
10 mg	￥ 3,600.00
10mM * 1mL in DMSO	￥ 2,560.00

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生物活性

1-Azakenpaullone是一种有效的选择性GSK-3β抑制剂，IC50为18 nM，选择性比CDK1/cyclin B和CDK5/p25高100倍。

靶点信息

GSK-3α	GSK-3β

溶解度 *

In vitro	DMSO	58 mg/mL (176.74 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.47 mL	152.36 mL	304.73 mL
0.5 mM	6.09 mL	30.47 mL	60.95 mL
1 mM	3.05 mL	15.24 mL	30.47 mL
5 mM	0.61 mL	3.05 mL	6.09 mL

*The above data is based on the productmolecular weight 328.16. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14303
作用机制	Inhibitor (抑制剂)
M. Wt	328.16
Formula	C15H10BrN3O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	676596-65-9
SMILES	C1C2=C(C3=C(C=CC=N3)NC1=O)NC4=C2C=C(C=C4)Br