A 438079 hydrochloride

目录号: A14983

P2X7 receptor 拮抗剂

A 438079 hydrochloride

A 438079 hydrochloride Chemical Structure

CAS NO. 899431-18-6

A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂(抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9)。

库存: 现货

规格 价格 数量
10 mg
¥ 950.00
25 mg
¥ 2,150.00
50 mg
¥ 3,950.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

A 438079 hydrochloride是一种竞争性P2X7受体拮抗剂(抑制人重组P2X7细胞系中Ca2+流入的pIC50 = 6.9)。
靶点信息
P2X7 receptor
6.9(pIC50)
In vitro (25°C) DMSO 55 mg/mL (160.53 mM)
Water 55 mg/mL (160.53 mM)
Ethanol Warmed: 18 mg/mL (52.53 mM)
In vivo Saline 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.19 mL 145.94 mL 291.88 mL
0.5 mM 5.84 mL 29.19 mL 58.38 mL
1 mM 2.92 mL 14.59 mL 29.19 mL
5 mM 0.58 mL 2.92 mL 5.84 mL

*The above data is based on the productmolecular weight 342.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14983
作用机制 Antagonist (拮抗剂)
M. Wt 342.61
Formula C13H10Cl3N5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 899431-18-6
SMILES C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl

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