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A-770041是选择性口服活性src家族lck抑制剂；a-770041是lck (1 mm atp)的147 nm抑制剂，对fyn有300倍的选择性，fyn是t细胞信号传导中的另一种src家族激酶。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.08 mL | 80.42 mL | 160.84 mL |
| 0.5 mM | 3.22 mL | 16.08 mL | 32.17 mL |
| 1 mM | 1.61 mL | 8.04 mL | 16.08 mL |
| 5 mM | 0.32 mL | 1.61 mL | 3.22 mL |
*The above data is based on the productmolecular weight 621.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11288 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 621.75 |
| Formula | C34H39N9O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 869748-10-7 |
| Synonyms | A770041, A 770041 |
| SMILES | CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=C(C(=N3)C5=CC(=C(C=C5)NC(=O)C6=CC7=CC=CC=C7N6C)OC)C(=NC=N4)N |
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