A 922500

目录号: A11199

DGAT-1 抑制剂

A 922500

A 922500 Chemical Structure

CAS NO. 959122-11-3

922500是一种二酰基甘油酰基转移酶1(DGAT-1)抑制剂(人和小鼠DGAT-1的IC50值分别为7和24 nM)。

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
50 mg
¥ 4,000.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,280.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

922500是一种二酰基甘油酰基转移酶1(DGAT-1)抑制剂(人和小鼠DGAT-1的IC50值分别为7和24 nM)。
靶点信息
human DGAT-1 mouse DGAT-1 DGAT-2
7 nM24 nM53 μM
In vitro (25°C) DMSO 83 mg/mL (193.7 mM)
Water Insoluble
Ethanol Insoluble
In vivo 15% Captisol 19 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.69 mL 233.38 mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11199
作用机制 Inhibitor (抑制剂)
M. Wt 428.48
Formula C26H24N2O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 959122-11-3
Synonyms DGAT-1 Inhibitor 4a, A-922500, A922500
SMILES C1C[C@H]([C@@H](C1)C(=O)O)C(=O)C2=CC=C(C=C2)C3=CC=C(C=C3)NC(=O)NC4=CC=CC=C4

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