AG-120 (Ivosidenib)

Name: AG-120 (Ivosidenib)
SKU: A14386

目录号: A14386

IDH1 抑制剂

AG-120 (Ivosidenib) Chemical Structure

CAS NO. 1448346-63-1

AG-120 (Ivosidenib)是1型异柠檬酸脱氢酶（IDH1）的口服抑制剂，具有潜在的抗肿瘤活性。

库存：现货

规格	价格	数量
5 mg	￥ 1,200.00
10 mg	￥ 2,200.00
25 mg	￥ 4,500.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

AG-120 (Ivosidenib)是1型异柠檬酸脱氢酶（IDH1）的口服抑制剂，具有潜在的抗肿瘤活性。

溶解度 *

In vitro	DMSO	95 mg/mL (162.95 mM)
	Water	Insoluble
	Ethanol	95 mg/mL (162.95 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.15 mL	85.77 mL	171.54 mL
0.5 mM	3.43 mL	17.15 mL	34.31 mL
1 mM	1.72 mL	8.58 mL	17.15 mL
5 mM	0.34 mL	1.72 mL	3.43 mL

*The above data is based on the productmolecular weight 582.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14386
作用机制	Inhibitor (抑制剂)
M. Wt	582.97
Formula	C28H22ClF3N6O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1448346-63-1
Synonyms	AG120, AG 120, Ivosidenib
SMILES	C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N