AG-17

目录号: A11949

EGFR 抑制剂

AG-17

AG-17 Chemical Structure

CAS NO. 10537-47-0

AG-17是人表皮样癌细胞系A431中EGFR激酶的抑制剂,IC50值为460 μM,作用于PDGFR更有效,IC50值为0.5μM。

库存: 现货

规格 价格 数量
50 mg
¥ 600.00
100 mg
¥ 1,100.00
200 mg
¥ 2,000.00
500 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AG-17是人表皮样癌细胞系A431中EGFR激酶的抑制剂,IC50值为460 μM,作用于PDGFR更有效,IC50值为0.5μM。
靶点信息
PDGFR EGFR
0.5 μM460 μM
In vitro DMSO 51 mg/mL (180.6 mM)
Water Insoluble
Ethanol 51 mg/mL (180.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.41 mL 177.05 mL 354.11 mL
0.5 mM 7.08 mL 35.41 mL 70.82 mL
1 mM 3.54 mL 17.71 mL 35.41 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11949
作用机制 Inhibitor (抑制剂)
M. Wt 282.4
Formula C18H22N2O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 10537-47-0
Synonyms NSC 242557, RG-50872, GCP 5126, SF 6847, Tyrphostin AG-17, Malonoben, Tyrphostin 9
SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#N

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