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AGN 195183是RARα（Kd = 3 nM）的强效选择性激动剂，相对于AGN 193836具有增强的结合选择性。对RARβ/γ无活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.84 mL | 114.19 mL | 228.38 mL |
| 0.5 mM | 4.57 mL | 22.84 mL | 45.68 mL |
| 1 mM | 2.28 mL | 11.42 mL | 22.84 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.57 mL |
*The above data is based on the productmolecular weight 437.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16293 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 437.86 |
| Formula | C22H22ClF2NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 367273-07-2 |
| Synonyms | AGN195183, AGN-195183 |
| SMILES | CC1(CCC(C2=C1C=C(C(=C2Cl)O)C(=O)NC3=CC(=C(C(=C3)F)C(=O)O)F)(C)C)C |
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