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AM095是一种有效的LPA1受体拮抗剂，因为它抑制GTPβS与过量表达重组人或小鼠LPA1的中国仓鼠卵巢（CHO）细胞膜结合，IC50值分别为0.98和0.73μM，并且没有LPA1激动作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.9 mL | 104.5 mL | 209 mL |
| 0.5 mM | 4.18 mL | 20.9 mL | 41.8 mL |
| 1 mM | 2.09 mL | 10.45 mL | 20.9 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.18 mL |
*The above data is based on the productmolecular weight 478.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13981 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 478.47 |
| Formula | C27H23N2NaO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1345614-59-6 |
| Synonyms | AM 095, AM-095 |
| SMILES | CC1=NOC(=C1NC(=O)O[C@H](C)C2=CC=CC=C2)C3=CC=C(C=C3)C4=CC=C(C=C4)CC(=O)[O-].[Na+] |
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