AM251

Name: AM251
SKU: A12914

目录号: A12914

CB1 receptor 拮抗剂

Product Citations (1)

AM251 Chemical Structure

CAS NO. 183232-66-8

AM251是有效的CB1受体拮抗剂（IC50 = 8 nM，Ki = 7.49 nM），其选择性是CB2受体的306倍。

库存：现货

规格	价格	数量
10 mg	￥ 650.00
25 mg	￥ 1,250.00
50 mg	￥ 2,400.00
100 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 1,060.00

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生物活性

AM251是有效的CB1受体拮抗剂（IC50 = 8 nM，Ki = 7.49 nM），其选择性是CB2受体的306倍。

靶点信息

CB1

溶解度 *

In vitro (25°C)	DMSO	39 mg/mL (70.24 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.01 mL	90.05 mL	180.1 mL
0.5 mM	3.6 mL	18.01 mL	36.02 mL
1 mM	1.8 mL	9.01 mL	18.01 mL
5 mM	0.36 mL	1.8 mL	3.6 mL

*The above data is based on the productmolecular weight 555.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12914
作用机制	Antagonist (拮抗剂)
M. Wt	555.24
Formula	C22H21Cl2IN4O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	183232-66-8
Synonyms	AM 251, AM-251
SMILES	CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I