(+)-Apogossypol

目录号: A16316

Bcl-2 family 抑制剂

(+)-Apogossypol

(+)-Apogossypol Chemical Structure

CAS NO. 66389-74-0

(+)-Apogossypol是Bcl-2家族蛋白的有效抑制剂。与Bcl-2,Bcl-XL,Mcl-1,Bcl-W和Bcl-B上的BH3肽结合位点竞争,但与Bfl-1竞争,IC50为0.5至2μM。

库存: 现货

规格 价格 数量
5 mg
¥ 3,200.00
10 mg
¥ 5,800.00
50 mg
¥ 16,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

(+)-Apogossypol是Bcl-2家族蛋白的有效抑制剂。与Bcl-2,Bcl-XL,Mcl-1,Bcl-W和Bcl-B上的BH3肽结合位点竞争,但与Bfl-1竞争,IC50为0.5至2μM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.1 mL 216.2 mL
0.5 mM 4.32 mL 21.62 mL 43.24 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16316
作用机制 Inhibitor (抑制剂)
M. Wt 462.53
Formula C28H30O6
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 66389-74-0
Synonyms Apogossypol, NSC736630
SMILES CC(C=C1C(C(C)C)=C(O)C(O)=CC1=C2O)=[C@]2[C@@]3=C(C)C=C4C(C=C(O)C(O)=C4C(C)C)=C3O

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