Aromatase

Catalog No.Inhibitor Name Aromatase
A10523Letrozole
****
A10075Anastrozole
***
A10378Exemestane
***

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

8 个项目

每页

设置升序顺序
  1. Fulvestrant (Faslodex)

    Catalog No. A10410
    Quick View
    Aromatase 抑制剂
    Fulvestrant是一种雌激素受体拮抗剂,没有激动剂作用,它通过下调和降解雌激素受体发挥作用。 了解更多
  2. Chrysin

    Catalog No. A10209
    Quick View
    Aromatase 抑制剂
    Chrysin是从蓝色西番莲(Passiflora caerulea)中化学提取的天然黄酮。已经显示出诱导抗炎作用,最可能是通过抑制COX-2表达和通过IL-6信号传导。在啮齿动物体内研究中,发现了菊花素具有抗焦虑作用。 了解更多
  3. Alpha-Naphthoflavone

    Catalog No. A18474
    Quick View
    aromatase inhibitor
    Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. 了解更多
  4. Fadrozole hydrochloride

    Catalog No. A21258
    Quick View
    Aromatase inhibitor
    Fadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. 了解更多
  5. Anastrozole

    Catalog No. A10075
    Quick View
    Aromatase 抑制剂
    Anastrozole是第三代非甾体选择性芳香化酶抑制剂。与其他芳香酶抑制剂相比,它可能具有更高的选择性,没有任何内在的内分泌作用,并且对肾上腺类固醇的合成也没有明显的作用。 了解更多
  6. Exemestane

    Catalog No. A10378
    Quick View
    Aromatase 抑制剂
    Exemestane是一种口服类固醇芳香化酶抑制剂,除绝经后妇女的手术和/或放疗外,还用于ER阳性乳腺癌。 了解更多
  7. Letrozole

    Catalog No. A10523
    Quick View
    Aromatase 抑制剂
    Letrozole是芳香酶抑制剂。CGS 20267是一种新型的非甾体化合物,在体外(IC50为11.5 nM)和在体内(ED50为1-3μg/ kg p.o.)均能有效抑制芳香化酶。 了解更多
  8. Fadrozole

    Catalog No. A11088
    Quick View
    Aromatase 抑制剂
    Fadrozole是一种非甾体芳香化酶抑制剂,在体内和体内雌激素的生物合成中均表现出非常有效和选择性的抑制作用。 了解更多

8 个项目

每页

设置升序顺序
Rewards