Artesunate

Name: Artesunate
SKU: A10087

目录号: A10087

cytochrome oxidase 抑制剂

Artesunate Chemical Structure

CAS NO. 88495-63-0

Artesunate是用于治疗疟疾的青蒿素的半合成衍生物。它也被证明可以有效对抗其他寄生虫，例如肝吸虫。青蒿琥酯还显示出针对不同肿瘤类型的癌细胞系的细胞毒性作用。青蒿琥酯已显示出通过抑制类风湿关节炎成纤维细胞样滑膜细胞中的NF-B和PI3激酶/ Akt信号通路来抑制TNF诱导的促炎细胞因子的产生。

库存：现货

规格	价格	数量
50 mg	￥ 540.00
100 mg	￥ 870.00
10mM * 1mL in DMSO	￥ 740.00

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产品详情

生物活性

靶点信息

EXP1(a membrane glutathione S-transferase)

溶解度 *

In vitro	DMSO	69 mg/mL (179.49 mM)
	Water	Insoluble
	Ethanol	69 mg/mL (179.49 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.01 mL	130.07 mL	260.15 mL
0.5 mM	5.2 mL	26.01 mL	52.03 mL
1 mM	2.6 mL	13.01 mL	26.01 mL
5 mM	0.52 mL	2.6 mL	5.2 mL

*The above data is based on the productmolecular weight 384.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10087
作用机制	Inhibitor (抑制剂)
M. Wt	384.4
Formula	C19H28O8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	88495-63-0
SMILES	C[C@@H]1CC[C@H]2[C@H]([C@@H](O[C@H]3[C@@]24[C@H]1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C