AS703026 (Pimasertib)

目录号: A10089

MEK1/2 抑制剂

AS703026 (Pimasertib)

AS703026 (Pimasertib) Chemical Structure

CAS NO. 1236699-92-5

AS703026 (Pimasertib)是一种新型的,选择性的,口服可生物利用的MEK1/2抑制剂,可抑制MM细胞的生长和存活以及细胞因子诱导的破骨细胞分化。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 700.00
50 mg
¥ 1,800.00
100 mg
¥ 3,000.00
10mM * 1mL in DMSO
¥ 930.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AS703026 (Pimasertib)是一种新型的,选择性的,口服可生物利用的MEK1/2抑制剂,可抑制MM细胞的生长和存活以及细胞因子诱导的破骨细胞分化。
In vitro (25°C) DMSO 78 mg/mL (180.89 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC+0.25% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.19 mL 115.96 mL 231.91 mL
0.5 mM 4.64 mL 23.19 mL 46.38 mL
1 mM 2.32 mL 11.6 mL 23.19 mL
5 mM 0.46 mL 2.32 mL 4.64 mL

*The above data is based on the productmolecular weight 431.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10089
作用机制 Inhibitor (抑制剂)
M. Wt 431.2
Formula C15H15FIN3O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1236699-92-5
Synonyms AS-703026, MSC1936369B
SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CN=C2)C(=O)NC[C@@H](CO)O

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