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ATI-2341是针对C-X-C趋化因子受体4型（CXCR4）（EC50 = 194 nM）的pepducin，是一种变构激动剂，可激活抑制性异三聚体G蛋白（Gi），从而促进cAMP生成的抑制并诱导钙动员。
| In vitro | DMSO | 85 mg/mL (37.66 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (0.88 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 4.43 mL | 22.16 mL | 44.31 mL |
| 0.5 mM | 0.89 mL | 4.43 mL | 8.86 mL |
| 1 mM | 0.44 mL | 2.22 mL | 4.43 mL |
| 5 mM | 0.09 mL | 0.44 mL | 0.89 mL |
*The above data is based on the productmolecular weight 2256.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16351 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 2256.82 |
| Formula | C104H178N26O25S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1337878-62-2 |
| Synonyms | ATI 2341, ATI2341 |
| SMILES | CCCCCCCCCCCCCCCC(=O)NC(CCSC)C(=O)NCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC2=CC=C(C=C2)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)O |
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