购物车 0 ￥ 0.00
微信关注
申请试用装
  • 主页 /
  • 搜索结果：“axl”

“axl”的搜索结果

23 个项目

每页

设置降序顺序
  1. DS-1205b free base
    Quick View

    DS-1205b free base

    Catalog No. A22138
    Quick View
    inhibitor of AXL kinase
    DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. 了解更多
  2. ONO-7475
    Quick View

    ONO-7475

    Catalog No. A22226
    Quick View
    Axl/Mer inhibitor
    ONO-7475 is a potent, selective, and orally active Axl/Mer inhibitor with IC50 values of 0.7 nM and 1.0 nM, respectively. 了解更多
  3. CEP-40783
    Quick View

    CEP-40783

    Catalog No. A20331
    Quick View
    AXL/c-Met inhibitor
    CEP-40783 is a potent, selective and orally available inhibitor of AXL and c-Met with IC50 values of 7 nM and 12 nM, respectively. 了解更多
  4. BMS 777607
    Quick View

    BMS 777607

    Catalog No. A21638
    Quick View
    c-Met/Axl/Ron/Tyro3 inhibitor
    BMS 777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively. 了解更多
  5. S49076
    Quick View

    S49076

    Catalog No. A21407
    Quick View
    MET, AXL/MER, and FGFR1/2/3 inhibitor
    S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM. 了解更多
  6. Gilteritinib hemifumarate
    Quick View

    Gilteritinib hemifumarate

    Catalog No. A18235
    Quick View
    FLT3/AXL inhibitor
    Gilteritinib hemifumarate is a potent FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively. 了解更多
  7. R916562
    Quick View

    R916562

    Catalog No. A19374
    Quick View
    Axl/VEGFR2 抑制剂
    R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis. 了解更多
  8. Gilteritinib (ASP2215)
    Quick View

    Gilteritinib (ASP2215)

    Catalog No. A14411
    Quick View
    FLT3/Axl 抑制剂
    Gilteritinib (ASP2215)是一种有效的FLT3/AXL抑制剂，对具有AML突变或FLT3-ITD和FLT3-D835的AML具有有效的抗白血病活性。 了解更多
  9. XL092
    Quick View

    XL092

    Catalog No. A22468
    Quick View
    XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and MER, with IC50 values in cell-based assays of 15, 1.6, 3.4, and 7.2 nM respectively. 了解更多
  10. Cabozantinib S-malate
    Quick View

    Cabozantinib S-malate

    Catalog No. A11349
    Quick View
    multiple receptor tyrosine kinases inhibitor
    Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. 了解更多
  11. UNC2541
    Quick View

    UNC2541

    Catalog No. A18523
    Quick View
    Mer tyrosine kinase inhibitor
    UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor, binds in the MerTK ATP pocket, with an IC50 of 4.4 nM, more selective over Axl, Tyro3 and Flt3. UNC2541 inhibits phosphorylated MerTK (pMerTK; EC50, 510 nM). 了解更多
  12. Glesatinib hydrochloride
    Quick View

    Glesatinib hydrochloride

    Catalog No. A16257
    Quick View
    MET/Axl 抑制剂
    Glesatinib hydrochloride是MET和Axl受体酪氨酸激酶途径的抑制剂，当改变时，它们会驱动肿瘤的生长。 了解更多
  13. SGI-7079
    Quick View

    SGI-7079

    Catalog No. A15864
    Quick View
    Axl 抑制剂
    SGI-7079是一种新型的选择性Axl抑制剂，以剂量依赖的方式抑制肿瘤的生长，并且是克服EGFR抑制剂耐药性的潜在治疗靶标。 了解更多
  14. TP-0903
    Quick View

    TP-0903

    Catalog No. A15776
    Quick View
    AXL 抑制剂
    TP-0903是一种有效的选择性Axl激酶抑制剂，IC50为27 nM。 了解更多
  15. R428
    Quick View

    R428

    Catalog No. A13741
    Quick View
    Axl 抑制剂
    R428是Axl激酶的选择性小分子抑制剂，在转移性乳腺癌模型中显示出阻断肿瘤扩散和延长生存期的活性。 了解更多
  16. Picropodophyllin
    Quick View

    Picropodophyllin

    Catalog No. A12195
    Quick View
    Picropodophyllin是首个靶向口服小分子igf-1受体抑制剂，IC50为1 nM。对胰岛素受体无影响。 了解更多
  17. EMD-1214063
    Quick View

    EMD-1214063

    Catalog No. A11257
    Quick View
    c-Met 抑制剂
    EMD-1214063是MET酪氨酸激酶的抑制剂，IC50为4 nM，作用于c-Met比作用于IRAK4， TrkA， Axl， IRAK1和Mer选择性高200倍以上。具有潜在的抗肿瘤活性。它与MET酪氨酸激酶结合并破坏MET信号转导途径，这可能在过表达该激酶的肿瘤细胞中诱导凋亡。 了解更多
  18. SNS-314
    Quick View

    SNS-314

    Catalog No. A10851
    Quick View
    Aurora 抑制剂
    SNS-314 Mesylate是Aurora A，Aurora B和Aurora C的有效和选择性抑制剂，IC50分别为9 nM，31 nM和3 nM。 它对Trk A/B，Flt4，Fms，Axl，c-Raf和DDR2的效力较低。 阶段1。 了解更多
  19. Ningetinib
    Quick View

    Ningetinib

    Catalog No. A17042
    Quick View
    tyrosine kinase 抑制剂
    Ningetinib是一种多激酶抑制剂，可抑制c-Met，VEGFR2/KDR和Axl，IC50值分别为19、37和11 nM。 了解更多
  20. 2-D08
    Quick View

    2-D08

    Catalog No. A16852
    Quick View
    SUMO 抑制剂
    2-D08是细胞可渗透的，机械上独特的蛋白质sumoylation抑制剂。在生化测定中，它也抑制Axl，IRAK4，ROS1，MLK4，GSK3β，RET，KDR和PI3Kα，IC50值分别为0.49、3.9、5.3、9.8、11、11、17和35 nM。 了解更多
  21. NPS-1034
    Quick View

    NPS-1034

    Catalog No. A15917
    Quick View
    c-Met 抑制剂
    NPS-1034是双重Met/Axl抑制剂，IC50分别为48 nM和10.3 nM。 了解更多
  22. UNC-2025
    Quick View

    UNC-2025

    Catalog No. A15904
    Quick View
    Dual MER/FLT3 抑制剂
    UNC-2025是一种有效的且可生物利用的双重MER/FLT3抑制剂，IC50分别为0.74 nM和0.8 nM，选择性是Axl和Tyro3的20倍。 了解更多
  23. LDC1267
    Quick View

    LDC1267

    Catalog No. A13003
    Quick View
    TAM Receptor 抑制剂
    LDC1267是一种高选择性TAM（Tyro3，Axl和Mer）激酶抑制剂，对于Tyro3，Axl和Mer的IC50分别小于5 nM/8 nM/29 nM。 了解更多

23 个项目

每页

设置降序顺序
联系我们
ChinaChina

Adooq 中国 (南京百鑫德诺生物科技有限公司)

免费电话: 400-025-6535

企业QQ: 400-025-6535

www.adooq.cn

sales@adooq.cn

United StatesUnited States

Adooq Bioscience

Toll Free: (866) 930-6790

Fax: +1-323-606-8156

Email: sales@adooq.com

Not your Region? View all Distributors

FILTER BY:

购物选项

分类
  1. Epigenetics (1)
  2. PI3K / Akt / mTOR (1)
  3. Protein Tyrosine Kinases (14)
  4. Angiogenesis (5)
  5. Cell Cycle (1)
  6. Ubiquitin (1)
  7. Ready to Use Solution (1)
  8. Products On Sale (4)
作用机制
  1. Inhibitor (抑制剂) (18)
靶点
  1. Aurora A (1)
  2. Aurora B (1)
  3. Aurora C (1)
  4. Axl (1)
  5. FLT3 (2)
  6. Mer (1)
ADOOQ 产品质量保证
Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.

立即申请
Get Code
联系我们
查看FAQs

Adooq 公司

产品订购

技术资源

地址

© 2006-2019 AdooQ BioScience （南京百鑫德诺生物科技有限公司）. All Rights Reserved.
苏ICP备14027875号
Accept Payment
Rewards