AZ191

目录号: A14314

DYRK 抑制剂

AZ191

AZ191 Chemical Structure

CAS NO. 1594092-37-1

AZ191是一种有效的选择性DYRK1B抑制剂,IC50为17 nM,选择性比DYRK1A和DYRK2高5到110倍。

库存: 现货

规格 价格 数量
10 mg
¥ 900.00
25 mg
¥ 1,800.00
50 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 660.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AZ191是一种有效的选择性DYRK1B抑制剂,IC50为17 nM,选择性比DYRK1A和DYRK2高5到110倍。
靶点信息
Dyrk1B (Cell-free assay) DYRK1A (Cell-free assay) DYRK2 (Cell-free assay)
17 nM88 nM1890 nM
In vitro DMSO 81 mg/mL (188.58 mM)
Water Insoluble
Ethanol 1 mg/mL (2.32 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.28 mL 116.41 mL 232.82 mL
0.5 mM 4.66 mL 23.28 mL 46.56 mL
1 mM 2.33 mL 11.64 mL 23.28 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14314
作用机制 Inhibitor (抑制剂)
M. Wt 429.52
Formula C24H27N7O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1594092-37-1
Synonyms AZ 191, AZ-191
SMILES CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=CC(=N3)C4=CN(C5=C4C=CN=C5)C)OC

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