AZD8330

目录号: A10115

MEK 抑制剂

AZD8330

AZD8330 Chemical Structure

CAS NO. 869357-68-6

AZD8330是新型,选择性,非ATP竞争性MEK 1/2抑制剂,IC50为7 nM。阶段1。

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 2,000.00
50 mg
¥ 6,200.00
100 mg
¥ 10,800.00
10mM * 1mL in DMSO
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

AZD8330是新型,选择性,非ATP竞争性MEK 1/2抑制剂,IC50为7 nM。阶段1。
靶点信息
ERK phosphorylation MEK1/2
0.4 nM7 nM
In vitro (25°C) DMSO 88 mg/mL (190.79 mM)
Water Insoluble
Ethanol 88 mg/mL (190.79 mM)
In vivo 0.5% hydroxyethyl cellulose+0.1% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.68 mL 108.41 mL 216.83 mL
0.5 mM 4.34 mL 21.68 mL 43.37 mL
1 mM 2.17 mL 10.84 mL 21.68 mL
5 mM 0.43 mL 2.17 mL 4.34 mL

*The above data is based on the productmolecular weight 461.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10115
作用机制 Inhibitor (抑制剂)
M. Wt 461.2
Formula C16H17FIN3O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 869357-68-6
Synonyms AZD-8330
SMILES CC1=CC(=C(N(C1=O)C)NC2=C(C=C(C=C2)I)F)C(=O)NOCCO

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