Bendamustine HCl (SDX-105)

Name: Bendamustine HCl (SDX-105)
SKU: A10124

目录号: A10124

Bendamustine HCl (SDX-105) Chemical Structure

CAS NO. 3543-75-7

Bendamustine Hydrochloride (SDX-105)是一种小分子双功能DNA烷基化剂，结合了氮芥菜碱功能和嘌呤类似物结构。苯达莫司汀具有致密的破坏DNA的功能，使其与用作抗增殖剂的其他化合物区分开来，这些功能被认为可通过多种不同途径（包括凋亡和有丝分裂灾难）促进细胞死亡。

库存：现货

规格	价格	数量
25 mg	￥ 400.00
50 mg	￥ 700.00
100 mg	￥ 1,200.00
10mM * 1mL in DMSO	￥ 650.00

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产品详情

生物活性

靶点信息

DNA synthesis (Cell-free assay)

溶解度 *

In vitro (25°C)	DMSO	69 mg/mL (174.8 mM)
	Water	2 mg/mL (5.06 mM)
	Ethanol	15 mg/mL (37.99 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.34 mL	126.68 mL	253.36 mL
0.5 mM	5.07 mL	25.34 mL	50.67 mL
1 mM	2.53 mL	12.67 mL	25.34 mL
5 mM	0.51 mL	2.53 mL	5.07 mL

*The above data is based on the productmolecular weight 394.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10124
M. Wt	394.7
Formula	C16H21Cl2N3O2.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	3543-75-7
Synonyms	Ribomustin, Treanda, SDX-105, Treakisym
SMILES	CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl