BG45

目录号: A11361

HDAC 抑制剂

BG45

BG45 Chemical Structure

CAS NO. 926259-99-6

BG45是一种HDAC I类抑制剂,对HDAC3具有选择性(IC50 = 289 nM)。它抑制HDAC1,HDAC2和HDAC6的效力大大降低(IC50分别为2、2和> 20μM)。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 700.00
50 mg
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BG45是一种HDAC I类抑制剂,对HDAC3具有选择性(IC50 = 289 nM)。它抑制HDAC1,HDAC2和HDAC6的效力大大降低(IC50分别为2、2和> 20μM)。
靶点信息
HDAC3 HDAC1 HDAC2 HDAC6
289 nM2 μM2.2 μM>20 μM
In vitro DMSO 40 mg/mL (186.72 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (9.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.68 mL 233.4 mL 466.81 mL
0.5 mM 9.34 mL 46.68 mL 93.36 mL
1 mM 4.67 mL 23.34 mL 46.68 mL
5 mM 0.93 mL 4.67 mL 9.34 mL

*The above data is based on the productmolecular weight 214.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11361
作用机制 Inhibitor (抑制剂)
M. Wt 214.22
Formula C11H10N4O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 926259-99-6
Synonyms BG 45, BG-45
SMILES NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2

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