Biochanin A (4-Methylgenistein)

目录号: A10146

Biochanin A (4-Methylgenistein)

Biochanin A (4-Methylgenistein) Chemical Structure

CAS NO. 491-80-5

Biochanin A (4-Methylgenistein)是一种抗增殖和抗炎剂,可抑制iNOS的表达和脂多糖(LPS)诱导的巨噬细胞中一氧化氮的产生。此外,Biochanin A还具有阻断IκBα和p38 MAPK磷酸化的能力,从而阻止了NF-κB的活化。此外,已观察到生物chanin A抑制IL-6,IL-1β和TNF-α的产生。

库存: 现货

规格 价格 数量
200 mg
¥ 500.00
500 mg
¥ 800.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Biochanin A (4-Methylgenistein)是一种抗增殖和抗炎剂,可抑制iNOS的表达和脂多糖(LPS)诱导的巨噬细胞中一氧化氮的产生。此外,Biochanin A还具有阻断IκBα和p38 MAPK磷酸化的能力,从而阻止了NF-κB的活化。此外,已观察到生物chanin A抑制IL-6,IL-1β和TNF-α的产生。
靶点信息
FAAH (rat) FAAH (mouse) FAAH (human) EGFR
1.4 μM1.8 μM2.4 μM91.5 μM
In vitro DMSO 51 mg/mL (179.41 mM)
Water Insoluble
Ethanol 8 mg/mL (28.14 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.17 mL 175.87 mL 351.74 mL
0.5 mM 7.03 mL 35.17 mL 70.35 mL
1 mM 3.52 mL 17.59 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL

*The above data is based on the productmolecular weight 284.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10146
M. Wt 284.3
Formula C16H12O5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 491-80-5
Synonyms 4-Methylgenistein
SMILES COC1=CC=C(C=C1)C2=COC3=CC(=CC(=C3C2=O)O)O

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