BIX02188

目录号: A10150

MEK5 抑制剂

BIX02188

BIX02188 Chemical Structure

CAS NO. 1094614-84-2, 334949-59-6

BIX02188是一种有效的选择性MEK5抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,360.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BIX02188是一种有效的选择性MEK5抑制剂。
Targets
Target Value
MEK5IC50: 4.3nM
ERK5IC50: 810nM
TGFβR1IC50: 1.8μM
MEK1IC50: >6.3μM
MEK2IC50: >6.3μM
ERK1IC50: >6.3μM
JNK2IC50: >6.3μM
EGFRIC50: >6.3μM
STK16IC50: >6.3μM
In vitro (25°C) DMSO 39 mg/mL (94.54 mM)
Water Insoluble
Ethanol 3 mg/mL (7.27 mM)
In vivo 5% DMSO+40% PEG 300+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.45 mL 117.23 mL 234.47 mL
0.5 mM 4.69 mL 23.45 mL 46.89 mL
1 mM 2.34 mL 11.72 mL 23.45 mL
5 mM 0.47 mL 2.34 mL 4.69 mL

*The above data is based on the productmolecular weight 426.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10150
作用机制 Inhibitor (抑制剂)
M. Wt 426.5
Formula C26H26N4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1094614-84-2, 334949-59-6
Synonyms BIX-02188
SMILES CN(C)CC1=CC(=CC=C1)N/C(=C\2/C3=C(C=C(C=C3)C(=O)N)NC2=O)/C4=CC=CC=C4

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