BMS-345541

Name: BMS-345541
SKU: A12559

目录号: A12559

IKK2/IKK1 抑制剂

BMS-345541 Chemical Structure

CAS NO. 445430-58-0

BMS-345541是IKK-2和IKK-1催化亚基的高度选择性抑制剂，IC50为0.3 μM和4 μM。

库存：现货

规格	价格	数量
5 mg	￥ 800.00
10 mg	￥ 1,400.00
25 mg	￥ 2,800.00

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生物活性

BMS-345541是IKK-2和IKK-1催化亚基的高度选择性抑制剂，IC50为0.3 μM和4 μM。

靶点信息

IKK2 (Cell-free assay)	IKK1 (Cell-free assay)
0.3 μM	4 μM

溶解度 *

In vitro	DMSO	8 mg/mL (31.32 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	39.17 mL	195.83 mL	391.67 mL
0.5 mM	7.83 mL	39.17 mL	78.33 mL
1 mM	3.92 mL	19.58 mL	39.17 mL
5 mM	0.78 mL	3.92 mL	7.83 mL

*The above data is based on the productmolecular weight 255.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12559
作用机制	Inhibitor (抑制剂)
M. Wt	255.32
Formula	C14H17N5
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	445430-58-0
Synonyms	BMS345541, BMS 345541
SMILES	CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN