BMS-911543

目录号: A11241

JAK 抑制剂

BMS-911543

BMS-911543 Chemical Structure

CAS NO. 1271022-90-2

BMS-911543是一种有效的、选择性JAK2小分子抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
25 mg
¥ 3,800.00
50 mg
¥ 7,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMS-911543是一种有效的、选择性JAK2小分子抑制剂。
靶点信息
JAK2 SET-2 TYK2 JAK3 JAK1
1.1 nM60 nM66 nM75 nM360 nM
In vitro DMSO 36 mg/mL (83.23 mM)
Water Insoluble
Ethanol 22 mg/mL (50.86 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.12 mL 115.6 mL 231.2 mL
0.5 mM 4.62 mL 23.12 mL 46.24 mL
1 mM 2.31 mL 11.56 mL 23.12 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11241
作用机制 Inhibitor (抑制剂)
M. Wt 432.52
Formula C23H28N8O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1271022-90-2
Synonyms BMS911543, BMS 911543
SMILES CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6

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