Brivanib alaninate (BMS-582664)

目录号: A10162

VEGFR 抑制剂

Brivanib alaninate (BMS-582664)

Brivanib alaninate (BMS-582664) Chemical Structure

CAS NO. 649735-63-7

Brivanib alaninate (BMS-582664)是VEGFR和FGFR信号转导的双重酪氨酸激酶抑制剂。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,680.00
25 mg
¥ 3,680.00
50 mg
¥ 6,880.00
10mM * 1mL in DMSO
¥ 1,380.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Brivanib alaninate (BMS-582664)是VEGFR和FGFR信号转导的双重酪氨酸激酶抑制剂。
靶点信息
VEGFR2 Flk1 FGFR1 VEGFR1
25 nM89 nM148 nM380 nM
In vitro (25°C) DMSO 83 mg/mL (188 mM)
Water Insoluble
Ethanol 83 mg/mL (188 mM)
In vivo 0.5% methylcellulose+0.2% Tween 80 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10162
作用机制 Inhibitor (抑制剂)
M. Wt 441.5
Formula C22H24FN5O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 649735-63-7
Synonyms BMS582664
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C

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