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产品 1 到 50 共 2939个

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  1. Docosahexaenoic Acid

    Catalog No. A18205
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    Docosahexaenoic Acid (DHA) is an omega-3 fatty acid abundantly present brain and retina. It can be obtained directly from fish oil and maternal milk. 了解更多
  2. Corticosterone

    Catalog No. A14269
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    Corticosterone 是一种具有口服活性的,由肾上腺皮质产生的糖皮质激素,在调节边缘系统 (包括海马体、前额叶皮层和杏仁核) 的神经元功能方面起着重要作用。皮质酮可通过 SGK 诱导的 GDI 磷酸化增加 Rab 介导的 AMPAR 膜运输. 了解更多
  3. Avelumab

    Catalog No. A18234
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    PD-1/PD-L1
    Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody with potential antibody-dependent cell-mediated cytotoxicity. 了解更多
  4. Exendin-4

    Catalog No. A21580
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    glucagon-like peptide-1 receptor agonist
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多
  5. SR-717

    Catalog No. A22048
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    non-nucleotide STING agonist
    SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. 了解更多
  6. DT2216

    Catalog No. A22050
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    BCL-XL degrader
    DT2216 is a potent and selective BCL-XL degrader based on PROTAC technology. 了解更多
  7. BMVC-8C3O

    Catalog No. A22052
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    DNA G-quadruplexe (G4) ligand
    BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s. 了解更多
  8. TLR4-IN-C34

    Catalog No. A22057
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    TLR4 inhibitor
    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. 了解更多
  9. PF-04745637

    Catalog No. A22060
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    TRPV1 antagonist
    PF-04745637 is a TRPV1 antagonist. 了解更多
  10. Neuraminidase-IN-1

    Catalog No. A22065
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    neuraminidase inhibitor
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus. 了解更多
  11. GW280264X

    Catalog No. A22087
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    ADAM17 inhibitor
    GW280264X is an ADAM17 inhibitor. 了解更多
  12. G244-LM

    Catalog No. A22090
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    tankyrase 1/2 inhibitor
    G244-LM is a potent and specific tankyrase 1/2 inhibitor that inhibits Wnt signaling. 了解更多
  13. API-1

    Catalog No. A22093
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    Akt inhibitor
    API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis. 了解更多
  14. PD-089828

    Catalog No. A22103
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    ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR
    PD089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR with IC50 of 0.15 ?M, 1.76 ?M, and 5.47 ?M, respectively. 了解更多
  15. JCP174

    Catalog No. A22107
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    depalmitoylase inhibitor
    JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1. 了解更多
  16. PS210

    Catalog No. A22109
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    protein kinase PDK1 inhibitor
    PS210 is a substrate-selective protein kinase PDK1 inhibitor that acts by binding to the PIF-pocket allosteric docking site. 了解更多
  17. RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  18. BRD6688

    Catalog No. A22111
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    HDAC2 inhibitor
    BRD6688 is a selective inhibitor of HDAC2 that acts by enhancing the learning and memory processes. 了解更多
  19. GSK121 trifluoroacetate

    Catalog No. A22117
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    PAD4 inhibitor
    GSK121 trifluoroacetate is a selective inhibitor of PAD4. 了解更多
  20. RO5203648 hydrochloride

    Catalog No. A22118
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    partial agonist of Trace amine-associated receptor 1
    RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1). 了解更多
  21. BMS-986188

    Catalog No. A22124
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    Positive Allosteric Modulator of the delta-Opioid Receptor
    BMS-986188 is a novel Potent and Selective Positive Allosteric Modulator of the delta-Opioid Receptor. 了解更多
  22. TTK21

    Catalog No. A22131
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    CBP/p300 histone acetyltransferase activator
    TTK21 is a CBP/p300 histone acetyltransferase activator. 了解更多
  23. RGW 611

    Catalog No. A22135
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    anti-infective agent
    RGW 611, a morpholine derivative, is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. 了解更多
  24. Aka Lumine

    Catalog No. A22152
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    luciferin analogue
    Aka Lumine, a luciferin analogue, is a luciferase substrate emitting red, green, and blue light. The longest emission wavelength of Aka Lumine is recorded at 675 nm, which is within the NIR region. 了解更多
  25. SR-31747 free base

    Catalog No. A22199
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    immunosuppressive and anti-inflammatory properties
    SR-31747 free base is a sigma ligand with immunosuppressive and anti-inflammatory properties. 了解更多
  26. Zebularine

    Catalog No. A12721
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    DNA methyltransferase inhibitor
    Zebularine (NSC309132; 4-Deoxyuridine) is a DNA methyltransferase inhibitor. 了解更多
  27. L-2-Hydroxyglutaric acid disodium

    Catalog No. A22281
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    epigenetic modifier
    L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium, L-2-Hydroxyglutarate disodium, LGA, L-2HG) is an epigenetic modifier and a putative oncometabolite in kidney cancer that inhibits histone demethylases and hence promotes histone methylation. 了解更多
  28. Pyruvic acid

    Catalog No. A22290
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    organic chemical intermediate
    Pyruvic acid (Acetylformic acid) is an important organic chemical intermediate that plays a role in cardiomyocyte pathophysiology and therapy. 了解更多
  29. Tomatine

    Catalog No. A22293
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    precipitating agent
    Tomatine is an glycoalkaloid that occurs in the extract of leaves of wild tomato plants. It has been found to inhibit the growth of various fungi and bacteria. It is used as a precipitating agent for steroids. 了解更多
  30. 2-Phospho-L-ascorbic acid trisodium

    Catalog No. A22309
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    antioxidant
    2-Phospho-L-ascorbic acid trisodium acts as an antioxidant and a stimulator of hepatocyte growth factor (HGF) production. 了解更多
  31. BL-918

    Catalog No. A22311
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    ULK1 activator
    BL-918 is an orally active UNC-51-like kinase 1 (ULK1) activator with an EC50 of 24.14 nM. 了解更多
  32. Higenamine

    Catalog No. A22315
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    β2-AR agonist
    Higenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. 了解更多
  33. MCP110

    Catalog No. A22317
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    inhibitor of Ras/Raf-1 interaction
    MCP110 is an inhibitor of Ras/Raf-1 interaction. MCP110 blocks the interaction of Ras with Raf. MCP110 disrupts this interaction might can be used for the research of human tumors. 了解更多
  34. ABTL-0812

    Catalog No. A22321
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    antineoplastic agent
    ABTL-0812 (α-Hydroxylinoleic acid) induces endoplasmic reticulum (ER) stress-mediated autophagy. ABTL-0812 is a first-in-class small molecule with anti-cancer activity. 了解更多
  35. Remibrutinib

    Catalog No. A22322
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    BTK inhibitor
    Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC50 value of 1 nM. 了解更多
  36. SR-4835

    Catalog No. A22337
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    dual inhibitor of CDK12/CDK13
    SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). 了解更多
  37. AUDA

    Catalog No. A22346
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    sEH inhibitor
    AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively. AUDA has anti-inflammatory activity. 了解更多
  38. 7,4'-Di-O-methylapigenin

    Catalog No. A22349
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    antifungal
    The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifungal phytomedicines. 了解更多
  39. Avacopan

    Catalog No. A22202
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    selective C5aR antagonist
    Avacopan (CCX168) is an orally administered and selective C5a receptor (C5aR) antagonist. 了解更多
  40. Lycorine

    Catalog No. A22170
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    SCAP inhibitor
    Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15.24 nM. 了解更多
  41. Eurycomanone

    Catalog No. A22171
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    Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis. 了解更多
  42. Gentiopicroside

    Catalog No. A22172
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    antianti-inflammatoryand antioxidative effects
    Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 ?M and 22.8 ?M for CYP2A6; Gentiopicroside has antianti-inflammatoryand antioxidative effects. 了解更多
  43. Eleutheroside B1

    Catalog No. A22173
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    anti-human influenza virus efficacy
    Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 ?g/ml. Antiviral and anti-inflammatory activities. 了解更多
  44. Periplogenin

    Catalog No. A22174
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    anti-psoriatic agent
    Periplogenin is a naturally occurring furanocoumarin found in Angelica dahurica roots, with potent anti-psoriatic effects. Periplogenin induces adipocyte differentiation. 了解更多
  45. Oxyberberin

    Catalog No. A22175
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    natural alkaloid
    Berlambine is a natural alkaloid isolated from many plants. 了解更多
  46. Groenlandicine

    Catalog No. A22176
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    protoberberine alkaloid
    Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). 了解更多
  47. 6-Methoxydihydroavicine

    Catalog No. A22177
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    antiplatelet activities
    6-Methoxydihydroavicine is an alkaloid isolated from Zanthoxylum integrifoliolum. 6-Methoxydihydroavicine has antiplatelet activities and inhibits AA-, collagen- and PAF-induced platelet aggregation in vitro. 了解更多
  48. S-23

    Catalog No. A22178
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    selective androgen receptor modulator
    S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. 了解更多
  49. AC-262536

    Catalog No. A22179
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    selective androgen receptor (SAR) molecule
    AC-262536 is a selective androgen receptor (SAR) molecule. It has partial agonist activity with respect to testosterone and suppresses luteinizing hormone. 了解更多
  50. Practolol

    Catalog No. A22186
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    β1-adrenergic receptor antagonist
    Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias. 了解更多

产品 1 到 50 共 2939个

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