“AG 013736”的搜索结果

产品 1 到 50 共 3341个

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  1. Axitinib

    Catalog No. A10103
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    VEGFR 抑制剂
    Axitinib是一种小分子酪氨酸激酶抑制剂,可抑制多种靶标,包括VEGFR-1,VEGFR-2,VEGFR-3,血小板衍生生长因子受体(PDGFR)和cKIT(CD117)。 了解更多
  2. Auranofin

    Catalog No. A18996
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    Auranofin is a gold salt classified by the World Health Organization as an antirheumatic agent. It is a gold-thiol complex with anti-inflammatory and immunosuppressive actions. 了解更多
  3. Thrombin

    Catalog No. A18861
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    digest GST-tagged proteins
    Thrombin is a trypsin-like allosteric serine protease. Thrombin enables site-specific cleavage of fusion proteins with an accessible Thrombin recognition sequence and can be used to digest GST-tagged proteins. 了解更多
  4. Angiotensin III

    Catalog No. A18943
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    angiotensin 1 (AT1) and AT2 receptor agonist
    Angiotensin III is an angiotensin 1 (AT1) and AT2 receptor agonist. 了解更多
  5. Melanin

    Catalog No. A19576
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    unique pigment
    Melanin is a unique pigment with myriad functions. It is multifunctional, providing defense against environmental stresses such as ultraviolet (UV) light, oxidizing agents and ionizing radiation. 了解更多
  6. Saponins

    Catalog No. A16691
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    Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi. 了解更多
  7. Hyaluronidase

    Catalog No. A18232
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    local anesthetic additive
    Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive. 了解更多
  8. Cinnamylamine

    Catalog No. A20835
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    Cinnamylamine can be used for the preparation of Tranylcypromine, a drug that acts as a nonselective and irreversible inhibitor of the enzyme monoamine oxidase (MAO), and is used as an antidepressant and anxiolytic agent. 了解更多
  9. IRL-1620

    Catalog No. A21080
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    endothelin receptor type B (ETB) agonist
    IRL-1620 is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM. 了解更多
  10. Exendin-4

    Catalog No. A21580
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    glucagon-like peptide-1 receptor agonist
    Exendin-4 (Exenatide), a 39 amino acid peptide, is a long-acting glucagon-like peptide-1 receptor agonist with an IC50 of 3.22 nM. 了解更多
  11. SR-717

    Catalog No. A22048
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    non-nucleotide STING agonist
    SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. 了解更多
  12. Sulopenem

    Catalog No. A22051
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    beta-lactamase inhibitor
    Sulopenem (CP-70429) is an orally active, potent inhibitor of beta-lactamase. Sulopenem is a parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. 了解更多
  13. Mizagliflozin

    Catalog No. A22056
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    SGLT1 inhibitor
    Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. 了解更多
  14. DIMBOA

    Catalog No. A22058
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    antifungal agent
    Dimboa is an antifungal agent used in crops. 了解更多
  15. PF-04745637

    Catalog No. A22060
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    TRPV1 antagonist
    PF-04745637 is a TRPV1 antagonist. 了解更多
  16. Neuraminidase-IN-1

    Catalog No. A22065
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    neuraminidase inhibitor
    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus. 了解更多
  17. BAY 2416964

    Catalog No. A22067
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    aryl hydrocarbon receptor (AHR) antagonist
    BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. 了解更多
  18. CWP232228

    Catalog No. A22070
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    Wnt/β-catenin signaling inhibitor
    CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. 了解更多
  19. CYM50308

    Catalog No. A22072
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    sphingosine-1-phosphate receptor 4 (S1P4-R) agonist
    CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. 了解更多
  20. CRANAD-2

    Catalog No. A22076
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    near-infrared (NIR) probe
    CRANAD-2 is a curcumin-derivatized near-infrared (NIR) probe that meets all the requirements for a NIR contrast agent for the detection of Abeta plaques both in vitro and in vivo. 了解更多
  21. BMS453

    Catalog No. A22082
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    RARβ agonist
    BMS453 (BMS-189453), a synthetic retinoid, is a RARβ agonist and a RARα/RARγ antagonist. 了解更多
  22. 4BP-TQS

    Catalog No. A22084
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    neuronal nicotinic acetylcholine receptors agonist
    4BP-TQS is an allosteric agonist of α7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs). 了解更多
  23. B355252

    Catalog No. A22086
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    neuroprotective agent
    B355252 is a neuroprotective agent potentiating nerve growth factor (NGF)-induced neurite outgrowth. 了解更多
  24. ML191

    Catalog No. A22088
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    GPR55 antagonist
    ML191 (CCG-152883, CID-23612552) is an antagonist of GPR55 with EC50 of 1.076 ?M in U2OS cells overexpressing GPR55. 了解更多
  25. NIBR-0213

    Catalog No. A22099
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    S1P(1) antagonist
    NIBR-0213 is a potent and selective antagonist of S1P(1) with efficacy in experimental autoimmune encephalomyelitis. 了解更多
  26. SR8278

    Catalog No. A22100
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    nuclear heme receptor REV-ERB synthetic antagonist
    SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. 了解更多
  27. CRANAD-28

    Catalog No. A22102
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    two-photon imaging probe
    CRANAD-28, a blood brain barrier (BBB) penetrable two-photon imaging probe, acts by labelling plaques and cerebral amyloid angiopathies (CAAs). 了解更多
  28. RH01687

    Catalog No. A22110
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    β-cell protector
    RH01687 is a potent β-cell protector that exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress. 了解更多
  29. Creatine riboside

    Catalog No. A22112
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    urinary metabolite
    Creatine riboside is a urinary metabolite and is a diagnostic and prognostic biomarker of lung cancer. 了解更多
  30. ONO-8130

    Catalog No. A22113
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    antagonist of EP1 receptor
    ONO-8130 is an orally available antagonist of EP1 receptor. 了解更多
  31. MSBN

    Catalog No. A22114
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    fluorogenic probe
    MSBN is a highly selective fluorogenic probe for thiols, selectively imaging thiols in live cells and specifically label protein thiols with a turn-on signal to determine diverse reversible protein thiol modifications. 了解更多
  32. Cytosporone B

    Catalog No. A22115
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    nuclear orphan receptor Nur77/NR4A1 agonist
    Cytosporone B (Csn-B; Dothiorelone G) is a naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with an EC50 of 0.278 nM. 了解更多
  33. RO5203648 hydrochloride

    Catalog No. A22118
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    partial agonist of Trace amine-associated receptor 1
    RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1). 了解更多
  34. FLTX1

    Catalog No. A22120
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    antiestrogenic properties
    FLTX1 is a fluorescent Tamoxifen derivative that can specifically label intracellular Tamoxifen-binding sites (estrogen receptors) under permeabilized and non-permeabilized conditions. FLTX1 exhibits the potent antiestrogenic properties of Tamoxifen in breast cancer cells. FLTX1 is devoid of the estrogenic agonistic effect on the uterus. 了解更多
  35. Epiblastin A

    Catalog No. A22121
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    inhibitor of Casein Kinase 1 (CK1)
    Epiblastin A is an inhibitor of Casein Kinase 1 (CK1) that engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). 了解更多
  36. BMS-986187

    Catalog No. A22125
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    positive allosteric modulator (PAM) of the δ-opioid receptor and a G-protein-biased allosteric agonist
    BMS-986187 is a potent and selective positive allosteric modulator (PAM) of the δ-opioid receptor and a G-protein-biased allosteric agonist. 了解更多
  37. PythiDC

    Catalog No. A22127
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    inhibitor of collagen prolyl 4-hydroxylase
    PythiDC is a selective inhibitor of collagen prolyl 4-hydroxylase. 了解更多
  38. BGC201531

    Catalog No. A22130
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    EP4 antagonist
    BGC201531, also known as GTPL3380 and AP-1531, is a EP4 antagonist for the treatment of acute migraine. 了解更多
  39. RGW 611

    Catalog No. A22135
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    anti-infective agent
    RGW 611, a morpholine derivative, is an impurity of Nimorazole, which is an anti-infective agent against anaerobic bacteria and protozoa. 了解更多
  40. MSA-2

    Catalog No. A22139
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    non-nucleotide STING agonist
    MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. 了解更多
  41. Pyrimorph

    Catalog No. A22144
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    fungicide
    Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. 了解更多
  42. Soporidine

    Catalog No. A22145
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    strigolactone (SL) antagonist
    Soporidine is a strigolactone (SL) antagonist and inhibitor of germination in their biological assays. It binds AtHTL and specifically interferes with SL signaling. 了解更多
  43. AA41612

    Catalog No. A22147
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    antagonist of melanopsin-mediated phototransduction
    AA41612 is an antagonist of melanopsin-mediated phototransduction. 了解更多
  44. ERDRP-0519

    Catalog No. A22150
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    inhibitor of polymerase
    ERDRP-0519 is an orally available inhibitor of polymerase that shows efficacy against a lethal morbillivirus infection in a large animal model. 了解更多
  45. Nicomol

    Catalog No. A22154
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    antilipidemic agent
    Nicomol is a niacin derivative that exhibits antilipidemic activity. 了解更多
  46. Cetraxate Hydrochloride

    Catalog No. A22155
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    mucosal protective agent and an anti-ulcer drug
    Cetraxate (DV-1006) Hydrochloride (HCl) is a mucosal protective agent and an anti-ulcer drug candidate. Cetraxate raises levels of calcitonin gene-related peptide and substance P in human plasma. 了解更多
  47. Adenosine amine congener

    Catalog No. A22193
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    A1 adenosine receptor agonist
    Adenosine amine congener (ADAC) is a selective A1 adenosine receptor agonist, can ameliorate noise- and Cisplatin-induced cochlear injury. 了解更多
  48. Clobenpropit dihydrobromide

    Catalog No. A22263
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    histamine H3R antagonist/inverse agonist
    Clobenpropit dihydrobromide is a potent histamine H3R antagonist/inverse agonist with a pEC50 of 8.07 for histamine H3LR. 了解更多
  49. A 784168

    Catalog No. A22264
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    antagonist of Vanilloid receptor type 1
    A-784168 is a potent and selective antagonist of Vanilloid receptor type 1 (TRPV1). 了解更多
  50. 5-HT3 antagonist-4i

    Catalog No. A22265
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    5-HT3 receptor antagonist
    5-HT3 antagonist-4i is a 5-HT3 receptor antagonist which modulates the serotonergic system. 了解更多

产品 1 到 50 共 3341个

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页面:
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