CCT137690

Name: CCT137690
SKU: A11081

目录号: A11081

Aurora Kinase 抑制剂

CCT137690 Chemical Structure

CAS NO. 1095382-05-0

CCT137690是Aurora A，Aurora B和Aurora C的高度选择性抑制剂，IC50为15 nM，25 nM和19 nM。它对hERG离子通道影响很小。

库存：现货

规格	价格	数量
5 mg	￥ 850.00
10 mg	￥ 1,100.00
50 mg	￥ 4,000.00
100 mg	￥ 6,250.00

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生物活性

CCT137690是Aurora A，Aurora B和Aurora C的高度选择性抑制剂，IC50为15 nM，25 nM和19 nM。它对hERG离子通道影响很小。

靶点信息

Aurora A	Aurora C	Aurora B
15 nM	19 nM	25 nM

溶解度 *

In vitro (25°C)	DMSO	4 mg/mL (7.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.13 mL	90.66 mL	181.32 mL
0.5 mM	3.63 mL	18.13 mL	36.26 mL
1 mM	1.81 mL	9.07 mL	18.13 mL
5 mM	0.36 mL	1.81 mL	3.63 mL

*The above data is based on the productmolecular weight 551.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11081
作用机制	Inhibitor (抑制剂)
M. Wt	551.5
Formula	C26H31BrN8O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1095382-05-0
Synonyms	CCT-137690
SMILES	CC1=CC(=NO1)CN2CCN(CC2)C3=C4C(=NC=C3Br)N=C(N4)C5=CC=C(C=C5)N6CCN(CC6)C