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￥ 0.00 Cell Metabolism
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MA-0204
Catalog No. A19031 PPARδ modulatorMA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD). 了解更多 -
Leriglitazone
Catalog No. A18636 PPAR gamma agonistLeriglitazone is a peroxisome proliferator activated receptor (PPAR) gamma agonist. 了解更多 -
Chiglitazar
Catalog No. A12701 PPARα/γ dual agonistChiglitazar is a PPARα/γ dual agonist, with EC50s of 1.2, 0.08, 1.7 μM for PPARα, PPARγ and PPARδ, respectively. 了解更多 -
Cilostamide
Catalog No. A13596 -
GSK256066 2,2,2-trifluoroacetic acid
Catalog No. A15097 PDE 抑制剂GSK256066是一种选择性PDE4B（与A-D型同等亲和力）抑制剂，IC50为3.2 pM，对PDE1/2/3/5/6的选择性> 380,000倍，对PDE4B与PDE7的选择性> 2500倍。 了解更多 -
Nortadalafil
Catalog No. A15191 PDE5 抑制剂Nortadalafil是去甲基他达拉非，它是一种PDE5抑制剂，目前以药丸形式销售，用于治疗勃起功能障碍（ED），名称为Cialis。并以Adcirca为名，用于治疗肺动脉高压。 了解更多 -
Olprinone Hydrochloride
Catalog No. A15198 -
TAK-063
Catalog No. A15799 -
Sildenafil
Catalog No. A12631 PDE5 抑制剂Sildenafil是选择性磷酸二酯酶5（PDE5）抑制剂之一（IC50 = 5.22 nM），被认为是治疗勃起功能障碍的最佳方法。 了解更多 -
PDE-9 inhibitor
Catalog No. A11532 -
AN3199
Catalog No. A12228 -
PF-05180999
Catalog No. A13006 PDE2A inhibitorPF-05180999 is a phosphodiesterase 2A (PDE2A) inhibitor, with an IC50 of 1.6 nM. 了解更多 -
Sildenafil citrate
Catalog No. A10841 PDE5 inhibitorSildenafil citrate is a potent phosphodiesterase type 5 (PDE5) inhibitor with IC50 of 5.22 nM. 了解更多 -
Mirodenafil dihydrochloride
Catalog No. A18047 PDE-5 inhibitorMirodenafil dihydrochloride (SK3530 dihydrochloride) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多 -
D159687
Catalog No. A21228 -
PF-04957325
Catalog No. A21246 PDE8 inhibitorPF-04957325 is a highly potent and selective PDE8 inhibitor, with IC50s of 0.7 nM and 0.3 nM for PDE8A and PDE8B, respectively. 了解更多 -
Mirodenafil
Catalog No. A21260 PDE-5 inhibitorMirodenafil(SK3530) is a phosphodiesterase type 5 (PDE-5) inhibitor developed for the treatment of erectile dysfunction. 了解更多 -
Saterinone hydrochloride
Catalog No. A21402 PDE3 inhibitorSaterinone hydrochloride is a phosphodiesterase III (PDE III) inhibitor. 了解更多 -
BAY 73-6691 racemate
Catalog No. A21745 PDE9 inhibitorBAY 73-6691 racemate is a phosphodiesterase 9 inhibitor extracted from patent WO 2017070293 A1. 了解更多 -
VP3.15 dihydrobromide
Catalog No. A21789 PDE7/GSK3 inhibitorVP3.15 dihydrobromide is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. 了解更多 -
TP-10
Catalog No. A21935 -
ITI214 free base
Catalog No. A21947 picomolar PDE1 inhibitorITI-214 (free base) is a picomolar PDE1 inhibitor with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters, and ion channels, exhibits potent PDE1 inhibitory activity (Ki = 58 pM). 了解更多 -
Deltasonamide 2
Catalog No. A21970 PDEδ inhibitorDeltasonamide 2 is a competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. 了解更多 -
Deltasonamide 2 (TFA)
Catalog No. A21979 PDEδ inhibitorDeltasonamide 2 TFA is competitive, high affinity PDEδ inhibitor with a Kd of ~385 pM. 了解更多 -
Cilostazol
Catalog No. A10217 -
Pimobendan (Vetmedin)
Catalog No. A10733 -
PF-2545920
Catalog No. A11191 -
Ibudilast (KC-404)
Catalog No. A11019 -
Cilomilast (SB-207499)
Catalog No. A10216 PDE-4 抑制剂Cilomilast (SB-207499)可作为选择性磷酸二酯酶4抑制剂，具有抗炎作用。可针对与COPD相关的支气管收缩，粘液分泌过多和气道重塑。 了解更多 -
Hesperetin
Catalog No. A10449 PDE4 抑制剂Hesperetin是一种选择性磷酸二酯酶(PDE)4抑制剂，存在于中药“陈皮”中。橙皮素是一种柑橘类黄酮，据报道可以降低血浆胆固醇。橙皮素降低Hep-G2细胞中ACAT-2 mRNA的转录，并以剂量依赖的方式降低ApoB蛋白的合成。它也是类癌的潜在疗法。 了解更多 -
Apremilast (CC 10004)
Catalog No. A11289 PDE4 抑制剂Apremilast (CC 10004)是一种新型的PDE4抑制剂，可抑制人类风湿性滑膜细胞自发产生肿瘤坏死因子-α，并改善实验性关节炎。 了解更多 -
Bay 60-7550
Catalog No. A11326 -
Aminophylline
Catalog No. A10066 Adenosine receptor 拮抗剂Aminophylline是一种非选择性的腺苷受体拮抗剂和磷酸二酯酶抑制剂，能够逆转局部缺血引起的bradyasystole。 了解更多 -
Dipyridamole
Catalog No. A10319
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