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Cevipabulin (TTI-237)是一种抗微管剂，是三唑并嘧啶衍生物的合成小分子，具有潜在的抗肿瘤活性。TTI-237具有不同于其他长春花生物碱化合物作用的新颖作用机理，可在长春花部位特异性结合微管蛋白，并促进微管蛋白聚合成微管。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.51 mL | 107.57 mL | 215.14 mL |
| 0.5 mM | 4.3 mL | 21.51 mL | 43.03 mL |
| 1 mM | 2.15 mL | 10.76 mL | 21.51 mL |
| 5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 464.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12591 |
|---|---|
| M. Wt | 464.82 |
| Formula | C18H18ClF5N6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 849550-05-6 |
| Synonyms | TTI237, D06576 |
| SMILES | C[C@@H](C(F)(F)F)NC1=C(C(=NC2=NC=NN12)Cl)C3=C(C=C(C=C3F)OCCCNC)F |
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