CHIR-99021

目录号: A10199

GSK-3 抑制剂

CHIR-99021

CHIR-99021 Chemical Structure

CAS NO. 252917-06-9

CHIR99021是一种GSK-3α和GSK-3β抑制剂,IC50值分别为10和6.7 nM。

库存: 现货

规格 价格 数量
2 mg
¥ 450.00
5 mg
¥ 700.00
25 mg
¥ 1,800.00
100 mg
¥ 4,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CHIR99021是一种GSK-3α和GSK-3β抑制剂,IC50值分别为10和6.7 nM。
靶点信息
GSK-3β GSK-3α
6.7 nM10 nM
In vitro (25°C) DMSO Warmed: 9 mg/mL (19.33 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+ddH2O 3.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.49 mL 107.46 mL 214.92 mL
0.5 mM 4.3 mL 21.49 mL 42.98 mL
1 mM 2.15 mL 10.75 mL 21.49 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10199
作用机制 Inhibitor (抑制剂)
M. Wt 465.3
Formula C22H18Cl2N8
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 252917-06-9
Synonyms GSK-3 Inhibitor XVI, CT 99021, CHIR99021
SMILES CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N

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