Cilomilast (SB-207499)

目录号: A10216

PDE-4 抑制剂

Cilomilast (SB-207499)

Cilomilast (SB-207499) Chemical Structure

CAS NO. 153259-65-5

Cilomilast (SB-207499)可作为选择性磷酸二酯酶4抑制剂,具有抗炎作用。可针对与COPD相关的支气管收缩,粘液分泌过多和气道重塑。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
10 mg
¥ 1,380.00
50 mg
¥ 4,200.00
100 mg
¥ 6,800.00
10mM * 1mL in DMSO
¥ 1,110.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Cilomilast (SB-207499)可作为选择性磷酸二酯酶4抑制剂,具有抗炎作用。可针对与COPD相关的支气管收缩,粘液分泌过多和气道重塑。
靶点信息
In vitro (25°C) DMSO 64 mg/mL (186.36 mM)
Water Insoluble
Ethanol 47 mg/mL (136.85 mM)
In vivo 5% DMSO+95% Corn oil 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.12 mL 145.6 mL 291.21 mL
0.5 mM 5.82 mL 29.12 mL 58.24 mL
1 mM 2.91 mL 14.56 mL 29.12 mL
5 mM 0.58 mL 2.91 mL 5.82 mL

*The above data is based on the productmolecular weight 343.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10216
作用机制 Inhibitor (抑制剂)
M. Wt 343.4
Formula C20H25NO4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 153259-65-5
Synonyms SB207499, Ariflo, SB-207,499
SMILES COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3

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