微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
CL-387785是EGFR的不可逆抑制剂，IC50为370+/-120 pM；能够在功能水平上克服由T790M突变引起的抗药性。
靶点信息
| EGFR | ||||
| 370 pM |
| In vitro | DMSO | Warmed: 61 mg/mL (160 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.23 mL | 131.15 mL | 262.31 mL |
| 0.5 mM | 5.25 mL | 26.23 mL | 52.46 mL |
| 1 mM | 2.62 mL | 13.12 mL | 26.23 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.25 mL |
*The above data is based on the productmolecular weight 381.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13146 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 381.23 |
| Formula | C18H13BrN4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 194423-06-8 |
| Synonyms | WAY-EKI 785, CL387785, CL 387785, EKI785, WAY-EKI785, EKI 785, EKI-785 |
| SMILES | CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1 |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Erlotinib HCl
Erlotinib hydrochloride是一种可逆的酪氨酸激酶抑制剂，作用于表皮生长因子受体（EGFR）。
BMS 599626 (AC480)
BMS 599626 (AC480)是一种选择性的，高效效的HER1，HER2和HER4酪氨酸激酶抑制剂（IC50分别为22、32和190 nM），具有…
Lapatinib (free base)
Lapatinib (free base)是一种双重酪氨酸激酶抑制剂，是一种有效的EGFR和ErbB2抑制剂，在无细胞试验中IC50分别为1…
PD153035 (HCl salt)
PD153035 (HCl salt)是EGFR酪氨酸激酶活性的极其有效和特异的抑制剂。
Icotinib Hydrochloride
Icotinib hydrochloride是一种有效的特异性表皮生长因子受体（EGFR）酪氨酸激酶抑制剂（TKI），IC（50）为5 nM，…
Keywords:购买 CL-387785 (EKI-785) | CL-387785 (EKI-785) 供应商 | 订购 CL-387785 (EKI-785) | CL-387785 (EKI-785) 价格 | CL-387785 (EKI-785) 生产商 | 订单 CL-387785 (EKI-785) | CL-387785 (EKI-785) 代理商 | 购买 194423-06-8| 194423-06-8 供应商 | 订购 194423-06-8 | 194423-06-8 价格 | 194423-06-8 生产商 | 订单 194423-06-8 | 194423-06-8 代理商|buy CL-387785 (EKI-785) | CL-387785 (EKI-785) Supplier | purchase CL-387785 (EKI-785) | CL-387785 (EKI-785) cost | CL-387785 (EKI-785) manufacturer | order CL-387785 (EKI-785) | CL-387785 (EKI-785) distributor | buy 194423-06-8| 194423-06-8 Supplier | purchase 194423-06-8 | 194423-06-8 cost | 194423-06-8 manufacturer | order 194423-06-8 | 194423-06-8 distributor