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13 个项目
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CYP17-IN-1
Catalog No. A12622 CYP17 inhibitorCYP17-IN-1 (compound 9c) is a potent and orally active CYP17 inhibitor against rat and human CYP17 with IC50s of 15.8 and 20.1 nM. 了解更多 -
Seviteronel
Catalog No. A20996 CYP17 lyase inhibitorSeviteronel (VT-464) is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM) that demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity in a hamster model of androgen biosynthesis inhibition. 了解更多 -
TOK-001 (Galeterone)
Catalog No. A11138 -
Avasimibe (CI-1011)
Catalog No. A10102 CYP17 抑制剂Avasimibe (CI-1011)是口服可生物利用的酰基辅酶A：胆固醇O-酰基转移酶（ACAT）抑制剂，IC50分别为2.9 μM， 13.9 μM和26.5 μM。 了解更多 -
Abiraterone Acetate (CB7630)
Catalog No. A11058 -
Abiraterone (CB-7598)
Catalog No. A10020 -
Voriconazole (Vfend)
Catalog No. A10978 -
D4-abiraterone
Catalog No. A19987 androgen receptor antagonistD4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor. 了解更多 -
Abiraterone metabolite 1
Catalog No. A16992 Abiraterone metabolite 1是abiraterone的5β还原代谢产物。类固醇药物abiraterone可抑制CYP17A1，阻断雄激素的合成并延长前列腺癌的生存期。 了解更多 -
TAK-700 Salt (Orteronel Salt)
Catalog No. A13515 CYP17A1/androgen synthesis 抑制剂TAK-700 Salt (Orteronel Salt)是一种雄激素合成抑制剂。它选择性地抑制在睾丸，肾上腺和前列腺肿瘤组织中表达的酶CYP17A。 了解更多 -
TAK-700 (Orteronel)
Catalog No. A11044
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