Danoprevir (RG7227)

目录号: A10284

HCV NS3/4A protease 抑制剂

Danoprevir (RG7227)

Danoprevir (RG7227) Chemical Structure

CAS NO. 850876-88-9

Danoprevir (RG7227)是HCV NS3/4A丝氨酸蛋白酶的有效抑制剂。

库存: 现货

规格 价格 数量
2 mg
¥ 600.00
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
50 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 2,740.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Danoprevir (RG7227)是HCV NS3/4A丝氨酸蛋白酶的有效抑制剂。
靶点信息
HCV NS3/4A protease
0.2 nM-3.5 nM
In vitro DMSO 124 mg/mL (169.43 mM)
Water Insoluble
Ethanol 124 mg/mL (169.43 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.93 mL 69.65 mL 139.3 mL
0.5 mM 2.79 mL 13.93 mL 27.86 mL
1 mM 1.39 mL 6.96 mL 13.93 mL
5 mM 0.28 mL 1.39 mL 2.79 mL

*The above data is based on the productmolecular weight 717.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10284
作用机制 Inhibitor (抑制剂)
M. Wt 717.9
Formula C35H48FN5O8S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 850876-88-9
Synonyms RG7227, ITMN-191, RO5190591
SMILES CC(C)(C)OC(=O)N[C@H]1CCCCC/C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]3C[C@H](CN3C1=O)OC(=O)N4CC5=C(C4)C(=CC=C5)F)C(=O)NS(=O)(=O)C6CC6

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