Boceprevir (SCH-503034)
Catalog No. A11332
Boceprevir (SCH-503034)是一种蛋白酶抑制剂,可用于治疗C型肝炎基因型1。
- Ueda Y, .et al. Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems, Virus Res, 2017, May 2;235:37-48 PMID: 28322919
- Shirasaki T, .et al. Impaired interferon signaling in chronic hepatitis C patients with advanced fibrosis via the transforming growth factor beta signaling pathway., Hepatology., 2014, 60(5):1519-30 PMID: 24962339
Catalog Num | A11332 |
---|---|
M. Wt | 519.7 |
Formula | C27H45N5O5 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 394730-60-0 |
Synonyms | EBP 520, SCH 503034 |
SMILES | CC1([C@@H]2[C@H]1[C@H](N(C2)C(=O)[C@H](C(C)(C)C)NC(=O)NC(C)(C)C)C(=O)NC(CC3CCC3)C(=O)C(=O)N)C |
Boceprevir (SCH-503034)是一种蛋白酶抑制剂,可用于治疗C型肝炎基因型1。
In vitro | DMSO | 90 mg/mL (173.18 mM) | |
Water | Insoluble | ||
Ethanol | 90 mg/mL (173.18 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.24 mL | 96.21 mL | 192.42 mL |
0.5 mM | 3.85 mL | 19.24 mL | 38.48 mL |
1 mM | 1.92 mL | 9.62 mL | 19.24 mL |
5 mM | 0.38 mL | 1.92 mL | 3.85 mL |
*The above data is based on the productmolecular weight 519.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.