BAY 1000394 (Roniciclib)
Catalog No. A12742
BAY 1000394 (Roniciclib)是一种口服生物利用细胞周期蛋白依赖性激酶（CDK）抑制剂，具有潜在的抗肿瘤活性。
- Marzia Ognibene, .et al. Roniciclib down-regulates stemness and inhibits cell growth by inducing nucleolar stress in neuroblastoma, Sci Rep, 2020, 10: 12902 PMID: 32737364
- Xinan (Holly) Yang, .et al. A c-Myc-regulated stem cell-like signature in high-risk neuroblastoma: A systematic discovery (Target neuroblastoma ESC-like signature), Sci Rep, 2017, 7: 41 PMID: 28246384
| Catalog Num | A12742 |
|---|---|
| M. Wt | 430.44 |
| Formula | C18H21F3N4O3S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1223498-69-8 |
| Synonyms | BAY10-00394; BAY1000394 |
| SMILES | C[C@H]([C@@H](C)OC1=NC(=NC=C1C(F)(F)F)NC2=CC=C(C=C2)S(=N)(=O)C3CC3)O |
BAY 1000394 (Roniciclib)是一种口服生物利用细胞周期蛋白依赖性激酶（CDK）抑制剂，具有潜在的抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.23 mL | 116.16 mL | 232.32 mL |
| 0.5 mM | 4.65 mL | 23.23 mL | 46.46 mL |
| 1 mM | 2.32 mL | 11.62 mL | 23.23 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.65 mL |
*The above data is based on the productmolecular weight 430.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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