WH 4-023
Catalog No. A14117
WH-4-023是一种有效的选择性Lck/Src双重抑制剂,对Lck和Src激酶的IC50分别为2 nM/6 nM。
Catalog Num | A14117 |
---|---|
M. Wt | 568.67 |
Formula | C32H36N6O4 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 837422-57-8 |
Synonyms | WH-4-023,WH4-023 |
SMILES | CC1=C(C(=CC=C1)C)OC(=O)N(C2=C(C=C(C=C2)OC)OC)C3=NC(=NC=C3)NC4=CC=C(C=C4)N5CCN(CC5)C |
WH-4-023是一种有效的选择性Lck/Src双重抑制剂,对Lck和Src激酶的IC50分别为2 nM/6 nM。
Targets
Lck (Cell-free assay) | Src (Cell-free assay) | |||
2 nM | 6 nM |
In vitro (25°C) | DMSO | Warmed: 12 mg/mL (21.1 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 6 mg/mL (10.55 mM) | ||
In vivo | 5% DMSO+30% PEG 300+5% Tween 80+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.58 mL | 87.92 mL | 175.85 mL |
0.5 mM | 3.52 mL | 17.58 mL | 35.17 mL |
1 mM | 1.76 mL | 8.79 mL | 17.58 mL |
5 mM | 0.35 mL | 1.76 mL | 3.52 mL |
*The above data is based on the productmolecular weight 568.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.