Debio-1347 (CH5183284)

目录号: A14415

FGFR1/2/3 抑制剂

Debio-1347 (CH5183284)

Debio-1347 (CH5183284) Chemical Structure

CAS NO. 1265229-25-1

Debio-1347 (CH5183284)是成纤维细胞生长因子受体亚型1(FGFR-1),2(FGFR-2)和3(FGFR-3)的生物利用抑制剂,具有潜在的抗肿瘤活性。

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 850.00
25 mg
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Debio-1347 (CH5183284)是成纤维细胞生长因子受体亚型1(FGFR-1),2(FGFR-2)和3(FGFR-3)的生物利用抑制剂,具有潜在的抗肿瘤活性。
靶点信息
FGFR2 FGFR1 FGFR3 FGFR4
7.6 nM9.3 nM22 nM290 nM
In vitro DMSO 70 mg/mL (196.41 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.3 mL 280.6 mL
0.5 mM 5.61 mL 28.06 mL 56.12 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14415
作用机制 Inhibitor (抑制剂)
M. Wt 356.38
Formula C20H16N6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1265229-25-1
Synonyms Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
SMILES CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N

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