Deferasirox

Name: Deferasirox
SKU: A10293

目录号: A10293

Iron chelator

Product Citations (1)

Deferasirox Chemical Structure

CAS NO. 201530-41-8

Deferasirox是一种铁螯合剂，也是细胞色素P450 3A4诱导剂，细胞色素P450 2C8抑制剂和细胞色素P450 1A2抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 450.00
10 mg	￥ 650.00
25 mg	￥ 800.00
50 mg	￥ 1,250.00
10mM * 1mL in DMSO	￥ 960.00

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生物活性

Deferasirox是一种铁螯合剂，也是细胞色素P450 3A4诱导剂，细胞色素P450 2C8抑制剂和细胞色素P450 1A2抑制剂。

溶解度 *

In vitro (25°C)	DMSO	64 mg/mL (171.42 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
In vivo	5% DMSO+40% PEG 300+5%Tween 80 +50 % H2O	3.5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.78 mL	133.92 mL	267.84 mL
0.5 mM	5.36 mL	26.78 mL	53.57 mL
1 mM	2.68 mL	13.39 mL	26.78 mL
5 mM	0.54 mL	2.68 mL	5.36 mL

*The above data is based on the productmolecular weight 373.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10293
M. Wt	373.36
Formula	C21H15N3O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	201530-41-8
Synonyms	ICL-670, ICL-670A, CGP-72670
SMILES	C1=C/C(=C\2/N/C(=C\3/C=CC=CC3=O)/N(N2)C4=CC=C(C=C4)C(=O)O)/C(=O)C=C1