Dolutegravir Sodium

目录号: A16162

HIV integrase 抑制剂

Dolutegravir Sodium

Dolutegravir Sodium Chemical Structure

CAS NO. 1051375-19-9

Dolutegravir Sodium是一种HIV整合酶抑制剂(IC50 = 2.7 nM),对耐raltegravir的签名突变体Y143R,Q148K,N155H和G140S/Q148H具有中等活性。

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 950.00
50 mg
¥ 3,990.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Dolutegravir Sodium是一种HIV整合酶抑制剂(IC50 = 2.7 nM),对耐raltegravir的签名突变体Y143R,Q148K,N155H和G140S/Q148H具有中等活性。
靶点信息
HIV integrase
2.7 nM
In vitro DMSO 0.18 mg/mL (0.41 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.66 mL 113.29 mL 226.57 mL
0.5 mM 4.53 mL 22.66 mL 45.31 mL
1 mM 2.27 mL 11.33 mL 22.66 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16162
作用机制 Inhibitor (抑制剂)
M. Wt 441.36
Formula C20H18F2N3NaO5
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1051375-19-9
Synonyms DTG, GSK1349572
SMILES CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

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