Donepezil hydrochloride

Name: Donepezil hydrochloride
SKU: A10330

目录号: A10330

cholinesterase 抑制剂

Donepezil hydrochloride Chemical Structure

CAS NO. 120011-70-3

Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。

库存：现货

规格	价格	数量
25 mg	￥ 400.00
100 mg	￥ 800.00
200 mg	￥ 1,200.00

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生物活性

Donepezil hydrochloride是一种中枢可逆的乙酰胆碱酯酶抑制剂。

靶点信息

bAChE	hAChE
8.12 nM	11.6 nM

溶解度 *

In vitro (25°C)	DMSO	Insoluble
	Water	5 mg/mL (12.01 mM)
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.04 mL	120.19 mL	240.38 mL
0.5 mM	4.81 mL	24.04 mL	48.08 mL
1 mM	2.4 mL	12.02 mL	24.04 mL
5 mM	0.48 mL	2.4 mL	4.81 mL

*The above data is based on the productmolecular weight 416. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10330
作用机制	Inhibitor (抑制剂)
M. Wt	416
Formula	C24H29NO3.HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	120011-70-3
SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.Cl