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Doxapram能抑制TASK-1，TASK-3，TASK-1/TASK-3异二聚体通道功能，EC50分别为410 nM，37μM，9μM。Doxapram是一种呼吸刺激剂。静脉注射多沙普兰可刺激潮气量和呼吸频率的增加。
| In vitro | DMSO | 68 mg/mL (179.65 mM) | |
| Water | Insoluble | ||
| Ethanol | 68 mg/mL (179.65 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.42 mL | 132.09 mL | 264.19 mL |
| 0.5 mM | 5.28 mL | 26.42 mL | 52.84 mL |
| 1 mM | 2.64 mL | 13.21 mL | 26.42 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.28 mL |
*The above data is based on the productmolecular weight 378.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15961 |
|---|---|
| M. Wt | 378.52 |
| Formula | C24H30N2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 309-29-5 |
| Synonyms | AHR-619, AHR 619, AHR619 |
| SMILES | O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4 |
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