ELR510444

目录号: A15455

Microtubule Disruptor

ELR510444

ELR510444 Chemical Structure

CAS NO. 1233948-35-0

ELR510444是一种新型的微管破坏剂;抑制MDA-MB-231细胞增殖,IC50为30.9 nM;而不是P-糖蛋白药物转运蛋白的底物,并在过量表达ΔIII-微管蛋白的细胞系中保留活性。

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

ELR510444是一种新型的微管破坏剂;抑制MDA-MB-231细胞增殖,IC50为30.9 nM;而不是P-糖蛋白药物转运蛋白的底物,并在过量表达ΔIII-微管蛋白的细胞系中保留活性。
In vitro DMSO 72 mg/mL (195.4 mM)
Water Insoluble
Ethanol 24 mg/mL (65.13 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.14 mL 135.7 mL 271.39 mL
0.5 mM 5.43 mL 27.14 mL 54.28 mL
1 mM 2.71 mL 13.57 mL 27.14 mL
5 mM 0.54 mL 2.71 mL 5.43 mL

*The above data is based on the productmolecular weight 368.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15455
M. Wt 368.47
Formula C19H16N2O2S2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1233948-35-0
Synonyms ELR-510444, ELR 510444
SMILES CC1=CC=C(S(NC2=C(C=CC(C3=CC=C(S3)C#N)=C2)C)(=O)=O)C=C1

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