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Endocrinology / Hormones

产品 151 到 200 共 236个

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  1. Cilazapril monohydrate
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    Cilazapril monohydrate

    Catalog No. A11747
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    ACE 抑制剂
    Cilazapril monohydrate是哒嗪血管紧张素转换酶抑制剂（ACE抑制剂），用于治疗高血压和充血性心力衰竭。 了解更多
  2. Temocapril
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    Temocapril

    Catalog No. A11749
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    ACE 抑制剂
    Temocapril是一种ACE抑制剂。 了解更多
  3. Enalapril maleate
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    Enalapril maleate

    Catalog No. A10350
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    ACE 抑制剂
    Enalapril maleate是一种血管紧张素转换酶（ACE）抑制剂，用于治疗高血压和某些类型的慢性心力衰竭。 了解更多
  4. Enalaprilat dihydrate
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    Enalaprilat dihydrate

    Catalog No. A10351
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    RAAS 抑制剂
    Enalaprilat dihydrate是依那普利的活性代谢产物。它是第一种含二羧酸盐的ACE抑制剂，IC50为1.2 nM。 了解更多
  5. PD 123319 ditrifluoroacetate
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    PD 123319 ditrifluoroacetate

    Catalog No. A13201
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    angiotensin AT2 receptor 拮抗剂
    PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。 了解更多
  6. LCZ696 (Valsartan)
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    LCZ696 (Valsartan)

    Catalog No. A14206
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    angiotensin receptor-neprilysin 抑制剂
    LCZ696 (Valsartan)是一种生物利用型双效血管紧张素受体-中性溶血素抑制剂（ARNi），用于治疗高血压和心力衰竭。 了解更多
  7. Captopril disulfide
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    Captopril disulfide

    Catalog No. A13521
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    LTA4 hydrolase 抑制剂
    Captopril disulfide是LTA4水解酶的可逆竞争性抑制剂（IC50 = 11 M）。Captopril已被证明是血管紧张素转化酶-1（ACE1）的一种，而不是ACE2（IC50 = 22 nM）。 了解更多
  8. Angiotensin I (human, mouse, rat)
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    Angiotensin I (human, mouse, rat)

    Catalog No. A14859
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    Angiotensin I (human,mouse,rat)是由肾素对血管紧张素原的作用形成的。 了解更多
  9. Angiotensin (1-7)
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    Angiotensin (1-7)

    Catalog No. A14862
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    Angiotensin (1-7)是一种内源性肽片段，可以分别通过内切肽酶或羧肽酶从Ang I或Ang II产生。 了解更多
  10. Angiotensin II
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    Angiotensin II

    Catalog No. A14863
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    Angiotensin II是一种八肽激素，在心血管稳态中起着核心作用。 了解更多
  11. Angiotensin III (human, mouse)
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    Angiotensin III (human, mouse)

    Catalog No. A14864
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    Angiotensin III (human,mouse)是在血管紧张素II的N末端裂解形成的六肽，血管紧张素II是位于红细胞和大多数组织血管床中的血管紧张素酶在肾素-血管紧张素-醛固酮（RAAS）系统中的关键因素。 了解更多
  12. Angiotensin 1/2 (1-9)
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    Angiotensin 1/2 (1-9)

    Catalog No. A14873
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    Angiotensin 1/2 (1-9)是一种肽（ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS），包含从血管紧张素I/II肽转换而来的氨基酸1-9。 了解更多
  13. Acetyl Angiotensinogen (1-14), porcine
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    Acetyl Angiotensinogen (1-14), porcine

    Catalog No. A14883
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    Acetyl Angiotensinogen (1-14), porcine血管紧张素原基因编码的蛋白质被称为血管紧张素原或血管紧张素原的前体。 了解更多
  14. Angiotensin 1/2 (1-5)
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    Angiotensin 1/2 (1-5)

    Catalog No. A14886
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    Angiotensin 1/2 (1-5)是一种包含氨基酸1-5的肽，是从血管紧张素I/II转化而来的。 了解更多
  15. Angiotensin 1/2 (1-6)
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    Angiotensin 1/2 (1-6)

    Catalog No. A14887
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    Angiotensin 1/2 (1-6)是一种包含氨基酸1-6的肽，是从血管紧张素I/II肽转化而来的。 了解更多
  16. Angiotensin 1/2 + A (2 - 8)
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    Angiotensin 1/2 + A (2 - 8)

    Catalog No. A14888
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    Angiotensin 1/2 + A (2 - 8)有效的内源性血管收缩肽；血管紧张素（Ang）的衍生物II。 了解更多
  17. VTP-27999 2,2,2-trifluoroacetate
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    VTP-27999 2,2,2-trifluoroacetate

    Catalog No. A15281
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    Renin 抑制剂
    VTP-27999 2,2,2-trifluoroacetate是一种烷基胺肾素抑制剂。VTP-27999可用于高血压和末梢器官疾病。 了解更多
  18. Spinorphin
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    Spinorphin

    Catalog No. A15314
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    Enkephalin-degrading and ACE 抑制剂
    Spinorphin是一种内源性因子，对脑啡肽降解酶具有抑制作用。 了解更多
  19. EXP-3174
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    EXP-3174

    Catalog No. A15451
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    AT1 receptor 拮抗剂
    EXP-3174是一种有效的选择性非竞争性AT1受体拮抗剂，IC50值为37 nM。 了解更多
  20. MLN-4760
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    MLN-4760

    Catalog No. A16884
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    ACE2 抑制剂
    MLN-4760是血管紧张素转化（ACE2）抑制剂。在huMNC中，MLN-4760-B检测到63％的ACE2，选择性是ACE的28倍。 了解更多
  21. Chrysin
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    Chrysin

    Catalog No. A10209
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    Aromatase 抑制剂
    Chrysin是从蓝色西番莲（Passiflora caerulea）中化学提取的天然黄酮。已经显示出诱导抗炎作用，最可能是通过抑制COX-2表达和通过IL-6信号传导。在啮齿动物体内研究中，发现了菊花素具有抗焦虑作用。 了解更多
  22. Alpha-Naphthoflavone
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    Alpha-Naphthoflavone

    Catalog No. A18474
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    aromatase inhibitor
    Alpha-Naphthoflavone is a synthetic flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively. 了解更多
  23. Fadrozole hydrochloride
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    Fadrozole hydrochloride

    Catalog No. A21258
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    Aromatase inhibitor
    Fadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. 了解更多
  24. Anastrozole
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    Anastrozole

    Catalog No. A10075
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    Aromatase 抑制剂
    Anastrozole是第三代非甾体选择性芳香化酶抑制剂。与其他芳香酶抑制剂相比，它可能具有更高的选择性，没有任何内在的内分泌作用，并且对肾上腺类固醇的合成也没有明显的作用。 了解更多
  25. Exemestane
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    Exemestane

    Catalog No. A10378
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    Aromatase 抑制剂
    Exemestane是一种口服类固醇芳香化酶抑制剂，除绝经后妇女的手术和/或放疗外，还用于ER阳性乳腺癌。 了解更多
  26. Letrozole
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    Letrozole

    Catalog No. A10523
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    Aromatase 抑制剂
    Letrozole是芳香酶抑制剂。CGS 20267是一种新型的非甾体化合物，在体外（IC50为11.5 nM）和在体内（ED50为1-3μg/ kg p.o.）均能有效抑制芳香化酶。 了解更多
  27. Fadrozole
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    Fadrozole

    Catalog No. A11088
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    Aromatase 抑制剂
    Fadrozole是一种非甾体芳香化酶抑制剂，在体内和体内雌激素的生物合成中均表现出非常有效和选择性的抑制作用。 了解更多
  28. AZD5423
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    AZD5423

    Catalog No. A13249
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    nonsteroidal glucocorticoid receptor 激动剂
    AZD5423是新型的非甾体类糖皮质激素受体激动剂。 了解更多
  29. Fluorometholone
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    Fluorometholone

    Catalog No. A17651
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    glucocorticoid
    Fluorometholone is a glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. 了解更多
  30. AZD2906
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    AZD2906

    Catalog No. A18936
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    glucocorticoid receptor agonist
    AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats. AZD2906 shows IC50s of 2.2, 0.3, 41.6 and 7.5 nM at GR in human, rat PBMC and human, rat whole blood, respectively. 了解更多
  31. Betamethasone acibutate
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    Betamethasone acibutate

    Catalog No. A18697
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    glucocorticoid
    Betamethasone acibutate, derives from Betamethasone, is an acetate ester. Betamethasone acibutate is a glucocorticoid. 了解更多
  32. Glucocorticoid receptor agonist
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    Glucocorticoid receptor agonist

    Catalog No. A11431
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    Glucocorticoid receptor agonist
    Glucocorticoid receptor agonist is a potent Glucocorticoid receptor agonist. 了解更多
  33. Dexamethasone acetate
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    Dexamethasone acetate

    Catalog No. A16494
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    glucocorticoid receptor agonist
    Dexamethasone acetate (Dexamethasone 21-acetate) is a glucocorticoid receptor agonist. 了解更多
  34. Beclometasone dipropionate
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    Beclometasone dipropionate

    Catalog No. A17254
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    glucocorticoid agonist
    Beclometasone dipropionate is a potent glucocorticoid agonist; it is a prodrug of the free form, beclometasone. 了解更多
  35. Fosdagrocorat
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    Fosdagrocorat

    Catalog No. A21303
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    dissociated glucocorticoid receptor agonist
    Fosdagrocorat (PF-04171327) is a dissociated glucocorticoid receptor agonist. 了解更多
  36. Dagrocorat
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    Dagrocorat

    Catalog No. A21312
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    glucocorticoid receptor agonist
    Dagrocorat (PF-00251802) is a novel and dissociated glucocorticoid receptor agonist. 了解更多
  37. (S)-Mapracorat
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    (S)-Mapracorat

    Catalog No. A21528
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    glucocorticoid receptor agonist
    (S)-Mapracorat is a selective and less active glucocorticoid receptor agonist. 了解更多
  38. Mapracorat
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    Mapracorat

    Catalog No. A21953
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    glucocorticoid receptor agonist
    Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist. 了解更多
  39. Betamethasone dipropionate
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    Betamethasone dipropionate

    Catalog No. A10130
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    Glucocorticoid Receptor 激动剂
    Betamethasone Dipropionate是糖皮质激素类固醇，具有抗炎和免疫抑制特性。 了解更多
  40. Betamethasone valerate (Betnovate, Celestone)
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    Betamethasone valerate (Betnovate, Celestone)

    Catalog No. A10131
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    Betamethasone valerate是一种有效的糖皮质激素类固醇，具有抗炎和免疫抑制作用 了解更多
  41. Budesonide
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    Budesonide

    Catalog No. A10166
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    Budesonide是一种糖皮质激素类固醇，可用于治疗哮喘，非感染性鼻炎 了解更多
  42. Prednisolone acetate (Omnipred)
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    Prednisolone acetate (Omnipred)

    Catalog No. A11687
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    Prednisolone是合成的糖皮质激素，是皮质醇的衍生物，用于治疗各种炎症和自身免疫性疾病。 了解更多
  43. Deflazacort
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    Deflazacort

    Catalog No. A10294
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    Deflazacort是一种糖皮质激素，用作抗炎和免疫抑制剂。 了解更多
  44. Hydrocortisone(Cortisol)
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    Hydrocortisone(Cortisol)

    Catalog No. A10457
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    Hydrocortisone是肾上腺产生的类固醇激素或糖皮质激素。 了解更多
  45. Meprednisone (Betapar)
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    Meprednisone (Betapar)

    Catalog No. A10567
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    Meprednisone是糖皮质激素和泼尼松的甲基化衍生物。 了解更多
  46. Methylprednisolone
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    Methylprednisolone

    Catalog No. A10582
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    Methylprednisolone是一种凋亡诱导剂，并且在体外也能抑制人小细胞肺癌细胞的生长。 了解更多
  47. Prednisone (Adasone)
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    Prednisone (Adasone)

    Catalog No. A10752
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    Glucocorticoid Receptor 激动剂
    Prednisone (Adasone)可降低粘膜TNF-a的产生，肠道通透性和NF-kB表达水平。 了解更多
  48. Fluticasone propionate
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    Fluticasone propionate

    Catalog No. A11860
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    Fluticasone propionate是一种高亲和力的选择性糖皮质激素受体激动剂（Kd = 0.5 nM）。 了解更多
  49. RU43044
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    RU43044

    Catalog No. A14340
    Glucocorticoid receptor 拮抗剂
    RU43044在骨肉瘤细胞而非人乳腺癌细胞中发挥显着的激动剂活性并激活MMTV-Luc转录。 了解更多
  50. GW-870086
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    GW-870086

    Catalog No. A18343
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    Glucocorticoid receptor agonist
    GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB. 了解更多

产品 151 到 200 共 236个

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  1. Estrogen Receptors (49)
  2. Progesterone Receptors (16)
  3. Androgen Receptors (20)
  4. GPR (18)
  5. 5-alpha-reductase (5)
  6. Pregnane X Receptors (4)
  7. renin-angiotensin-aldosterone system (RAAS) (61)
  8. Aromatase (8)
  9. Glucocorticoid receptors (26)
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  13. Apelin Receptors (1)
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  1. Inhibitor (抑制剂) (42)
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