Epothilone A

目录号: A10359

Microtubule Associated 抑制剂

Epothilone A

Epothilone A Chemical Structure

CAS NO. 152044-53-6

Epothilone A 通过稳定紫杉醇结合位点处的微管形成而起作用,并导致细胞周期停滞在G2/M转变,从而导致细胞毒性。

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,400.00
25 mg
¥ 2,800.00
10mM * 1mL in DMSO
¥ 800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Epothilone A 通过稳定紫杉醇结合位点处的微管形成而起作用,并导致细胞周期停滞在G2/M转变,从而导致细胞毒性。
靶点信息
Tubulin
2 μM(EC0.01)
In vitro DMSO 92 mg/mL (186.36 mM)
Water Insoluble
Ethanol 92 mg/mL (186.36 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.28 mL 202.55 mL
0.5 mM 4.05 mL 20.26 mL 40.51 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10359
作用机制 Inhibitor (抑制剂)
M. Wt 493.7
Formula C26H39NO6S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 152044-53-6
Synonyms EpoA, Epothilone-A
SMILES C[C@H]1CCC[C@@H]2[C@@H](O2)C[C@H](OC(=O)C[C@@H](C(C(=O)[C@@H]([C@H]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C

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