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EPZ031686是SMYD3和MEKK2的非竞争性抑制剂，Ki = 1.2和1.1 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.92 mL | 84.59 mL | 169.18 mL |
| 0.5 mM | 3.38 mL | 16.92 mL | 33.84 mL |
| 1 mM | 1.69 mL | 8.46 mL | 16.92 mL |
| 5 mM | 0.34 mL | 1.69 mL | 3.38 mL |
*The above data is based on the productmolecular weight 591.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16375 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 591.09 |
| Formula | C26H34ClF3N4O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1808011-22-4 |
| Synonyms | EPZ-031686, EPZ 031686 |
| SMILES | ClC1=CC(N2)=C(CC2=O)C=C1C(N[C@@]3([H])C[C@@](N4S(CC(CC5)CCN5CCCC(F)(F)F)(=O)=O)([H])CC[C@@]4([H])C3)=O |
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