Forskolin

Name: Forskolin
SKU: A12917

目录号: A12917

PDE 抑制剂

Forskolin Chemical Structure

CAS NO. 66575-29-9

Forskolin是具有抗高血压，正性肌力和腺苷酸环化酶激活特性的细胞渗透性二萜。Forskolin 是一种有效的腺苷酸环化酶激活剂，结合到 I 型腺苷酸环化酶 IC50 为 41 nM，激活 I 型腺苷酸环化酶 EC50 为 0.5 μM。

库存：现货

规格	价格	数量
10 mg	￥ 500.00
25 mg	￥ 800.00
50 mg	￥ 1,200.00
100 mg	￥ 1,600.00
10mM * 1mL in DMSO	￥ 500.00

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产品详情

生物活性

靶点信息

Adenylyl cyclase (AC) (A wide variety of cell types)

溶解度 *

In vitro	DMSO	72 mg/mL (175.39 mM)
	Water	Insoluble
	Ethanol	33 mg/mL (80.39 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.36 mL	121.8 mL	243.6 mL
0.5 mM	4.87 mL	24.36 mL	48.72 mL
1 mM	2.44 mL	12.18 mL	24.36 mL
5 mM	0.49 mL	2.44 mL	4.87 mL

*The above data is based on the productmolecular weight 410.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12917
作用机制	Inhibitor (抑制剂)
M. Wt	410.51
Formula	C22H34O7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	66575-29-9
Synonyms	Coleonol, Colforsin
SMILES	CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O