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Fosamprenavir Calcium Salt 是抗逆转录病毒蛋白酶抑制剂amprenavir的磷酸酯前药，与母体分子相比具有更高的溶解度，并有可能减轻当前给药方案中的药丸负担；GW433908G是前药的钙盐。
| In vitro | DMSO | 93 mg/mL (149.12 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (4.81 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.03 mL | 80.17 mL | 160.34 mL |
| 0.5 mM | 3.21 mL | 16.03 mL | 32.07 mL |
| 1 mM | 1.6 mL | 8.02 mL | 16.03 mL |
| 5 mM | 0.32 mL | 1.6 mL | 3.21 mL |
*The above data is based on the productmolecular weight 623.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15089 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 623.67 |
| Formula | C25H34CaN3O9PS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 226700-81-8 |
| Synonyms | GW 433908G, Lexiva, GW433908G, GW-433908G |
| SMILES | CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2CCOC2)OP(=O)([O-])[O-])S(=O)(=O)C3=CC=C(C=C3)N.[Ca+2] |
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