Glimepiride

Name: Glimepiride
SKU: A10430

目录号: A10430

Kir6.2/SUR 抑制剂

Glimepiride Chemical Structure

CAS NO. 93479-97-1

Glimepiride是一种强效Kir6.2/SUR抑制剂，SUR1、SUR2A和SURB的IC50分别为3.0 nM、5.4 nM和7.3 nM，用于治疗2型糖尿病化合物。

库存：现货

规格	价格	数量
500 mg	￥ 600.00
1000 mg	￥ 1,000.00
2000 mg	￥ 1,800.00
5000 mg	￥ 4,000.00
10mM * 1mL in DMSO	￥ 600.00

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生物活性

Glimepiride是一种强效Kir6.2/SUR抑制剂，SUR1、SUR2A和SURB的IC50分别为3.0 nM、5.4 nM和7.3 nM，用于治疗2型糖尿病化合物。

靶点信息

SUR1	SUR2A	SUR2B
3 nM	5.4 nM	7.3 nM

溶解度 *

In vitro	DMSO	10 mg/mL (20.38 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.38 mL	101.91 mL	203.82 mL
0.5 mM	4.08 mL	20.38 mL	40.76 mL
1 mM	2.04 mL	10.19 mL	20.38 mL
5 mM	0.41 mL	2.04 mL	4.08 mL

*The above data is based on the productmolecular weight 490.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10430
作用机制	Inhibitor (抑制剂)
M. Wt	490.62
Formula	C24H34N4O5S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	93479-97-1
Synonyms	Amary
SMILES	CCC1=C(CN(C1=O)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCC(CC3)C)C