GSK-2193874

目录号: A14201

TRPV4 blocker

GSK-2193874

GSK-2193874 Chemical Structure

CAS NO. 1336960-13-4

GSK2193874被确定为选择性的口服活性TRPV4阻滞剂,可通过重组TRPV4通道和天然内皮TRPV4电流抑制Ca(2+)流入。

库存: 现货

规格 价格 数量
10 mg
¥ 1,300.00
25 mg
¥ 2,600.00
50 mg
¥ 4,250.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

GSK2193874被确定为选择性的口服活性TRPV4阻滞剂,可通过重组TRPV4通道和天然内皮TRPV4电流抑制Ca(2+)流入。
In vitro DMSO 95 mg/mL (137.35 mM)
Water Insoluble
Ethanol Warmed: 48 mg/mL (69.4 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.46 mL 72.29 mL 144.59 mL
0.5 mM 2.89 mL 14.46 mL 28.92 mL
1 mM 1.45 mL 7.23 mL 14.46 mL
5 mM 0.29 mL 1.45 mL 2.89 mL

*The above data is based on the productmolecular weight 691.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14201
作用机制 Blocker (阻断剂)
M. Wt 691.62
Formula C37H38BrF3N4O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1336960-13-4
Synonyms GSK 2193874, GSK2193874
SMILES C1CCN(CC1)C2CCN(CC2)CC3=C(N=C4C=C(C=CC4=C3C(=O)NC5(CC5)C6=CC=CC=C6)Br)C7=CC(=CC=C7)C(F)(F)F

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